Title:
SUCRALOSE PURIFICATION METHOD
Document Type and Number:
WIPO Patent Application WO/2022/067621
Kind Code:
A1
Abstract:
A sucralose purification method, sequentially comprising: putting sucralose in ultrapure water, heating for dissolving and then filtering, and extracting with an extraction solvent to remove non-polar impurities; evaporating an extracted recrystallization solution to concentrate same to a preset concentration; leaving the solution to stand at a preset temperature for a preset time to form sucralose crystal nuclei; carrying out programmed cooling on the recrystallization solution containing crystal nuclei to obtain a recrystallization solution containing a large amount of sucralose crystals; and centrifuging the recrystallization solution containing a large amount of sucralose crystals, washing with water, and drying to obtain sucralose crystals. Extraction and impurity removal are carried out at first, next, the formation of crystal nuclei is promoted, and then, the growth of crystals is accelerated by means of a secondary nucleation process to ensure full crystallization, such that the obtained sucralose crystals have a single crystal form, are completely crystallized, have a regular shape, extremely high purity, nice color, high accumulation density, and long storage time, and can meet the requirements of high-end products for sugar substitutes.
Inventors:
ZHOU RUI (CN)
ZHAO JINGANG (CN)
ZHENG XUELIAN (CN)
BU YONGFENG (CN)
CHEN CHAOHUI (CN)
ZHAO JINGANG (CN)
ZHENG XUELIAN (CN)
BU YONGFENG (CN)
CHEN CHAOHUI (CN)
Application Number:
PCT/CN2020/119233
Publication Date:
April 07, 2022
Filing Date:
September 30, 2020
Export Citation:
Assignee:
ANHUI JINHE IND CO LTD (CN)
International Classes:
C07H1/06; C07H5/02
Domestic Patent References:
| WO2008004246A1 | 2008-01-10 |
Foreign References:
| CN111138502A | 2020-05-12 | |||
| CN102336786A | 2012-02-01 | |||
| CN105037449A | 2015-11-11 | |||
| CN106083942A | 2016-11-09 | |||
| US20060188629A1 | 2006-08-24 | |||
| US7049435B2 | 2006-05-23 | |||
| US5498709A | 1996-03-12 | |||
| US4980463A | 1990-12-25 | |||
| CN101260126A | 2008-09-10 | |||
| CN1639179A | 2005-07-13 | |||
| CN101210034A | 2008-07-02 |
Other References:
See also references of EP 4206211A4
Attorney, Agent or Firm:
BEIJING LONGAN LAW FIRM (CN)
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