Title:
SULFONAMIDE COMPOUND OR SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/018544
Kind Code:
A1
Abstract:
Disclosed is a sulfonamide compound having a chemical structure characterized
in that the compound has an amide structure wherein a carbon atom in the amide binds
to a nitrogen atom in a sulfonamide through a lower alkylene, or a salt of the compound.
The compound or the salt has a potent antagonistic activity against an EP1 receptor
and is therefore useful as a therapeutic agent for a disease associated with an
EP1 receptor, particularly lower urinary tract symptom.
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Inventors:
KUBOTA HIDEKI (JP)
TODA SUSUMU (JP)
TSUKAMOTO ISSEI (JP)
FUKUDA YUTA (JP)
WAKAYAMA RYUTARO (JP)
ONO KAZUKI (JP)
WATANABE TORU (JP)
AZAMI HIDENORI (JP)
TODA SUSUMU (JP)
TSUKAMOTO ISSEI (JP)
FUKUDA YUTA (JP)
WAKAYAMA RYUTARO (JP)
ONO KAZUKI (JP)
WATANABE TORU (JP)
AZAMI HIDENORI (JP)
Application Number:
PCT/JP2007/065613
Publication Date:
February 14, 2008
Filing Date:
August 09, 2007
Export Citation:
Assignee:
ASTELLAS PHARMA INC (JP)
KUBOTA HIDEKI (JP)
TODA SUSUMU (JP)
TSUKAMOTO ISSEI (JP)
FUKUDA YUTA (JP)
WAKAYAMA RYUTARO (JP)
ONO KAZUKI (JP)
WATANABE TORU (JP)
AZAMI HIDENORI (JP)
KUBOTA HIDEKI (JP)
TODA SUSUMU (JP)
TSUKAMOTO ISSEI (JP)
FUKUDA YUTA (JP)
WAKAYAMA RYUTARO (JP)
ONO KAZUKI (JP)
WATANABE TORU (JP)
AZAMI HIDENORI (JP)
International Classes:
A61K31/216; A61K31/18; A61K31/195; A61K31/197; A61K31/198; A61K31/235; A61K31/24; A61K31/275; A61K31/341; A61K31/343; A61K31/381; A61K31/40; A61K31/4015; A61K31/404; A61K31/415; A61K31/4196; A61K31/423; A61K31/426; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/472; A61K31/4965; A61K31/50; A61K31/505; A61K31/5375; A61P13/02; A61P13/08; A61P13/10; A61P43/00; C07C311/21; C07C311/29; C07D207/27; C07D207/325; C07D209/08; C07D213/40; C07D213/68; C07D213/70; C07D213/79; C07D213/89; C07D215/12; C07D217/06; C07D231/12; C07D237/08; C07D239/26; C07D241/12; C07D249/08; C07D263/32; C07D263/58; C07D277/20; C07D277/28; C07D277/36; C07D295/12; C07D307/52; C07D307/81; C07D333/20; C07D333/34; C07D333/38; C07D333/40; C07D333/58; C07K7/00
Domestic Patent References:
| WO1998027053A1 | 1998-06-25 | |||
| WO2002072145A1 | 2002-09-19 | |||
| WO2002072564A1 | 2002-09-19 | |||
| WO2005000356A1 | 2005-01-06 | |||
| WO2000069465A1 | 2000-11-23 | |||
| WO1998027053A1 | 1998-06-25 | |||
| WO2002072564A1 | 2002-09-19 | |||
| WO2000050391A1 | 2000-08-31 | |||
| WO2002020463A2 | 2002-03-14 | |||
| WO2004033418A2 | 2004-04-22 |
Foreign References:
| JP2004520433A | 2004-07-08 | |||
| JP2002526517A | 2002-08-20 | |||
| US20050020646A1 | 2005-01-27 | |||
| JP2005206492A | 2005-08-04 |
Other References:
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"UROLOGICAL RESEARCH", (USA), vol. 18, no. 5, 1990, pages 349 - 52
"THE JOURNAL OF UROLOGY", (USA), vol. 153, no. 6, June 1995 (1995-06-01), pages 2034 - 8
JOURNAL OF THE JAPANESE UROLOGICAL ASSOCIATION, vol. 92, no. 2, February 2001 (2001-02-01), pages 304
KOBE, THE 89TH ANNUAL MEETING OF THE JAPANESE UROLOGICAL ASSOCIATION, 2001, pages MP-305
"ANESTHESIOLOGY", (USA), vol. 97, no. 5, November 2002 (2002-11-01), pages 1254 - 62
"ANESTHESIA AND ANALGESIA", (USA), vol. 95, no. 6, December 2002 (2002-12-01), pages 1708 - 12
"ANESTHESIA AND ANALGESIA", (USA), vol. 93, no. 4, October 2001 (2001-10-01), pages 1012 - 7
GASTROENTEROLOGY, vol. 124, no. 1, January 2003 (2003-01-01), pages 18 - 25
"Progress in Medicine"", LIFE SCIENCE MEDICAL, vol. 5, 1985, pages 2157 - 2161
"lyakuhin no Kaihatsu", BUNSHI SEKKEI, vol. 7, 1990, pages 163 - 198
"Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS
"Annals of the New York Academy of Science", vol. 51, 1949, pages: 660
THE JOURNAL OF NEUROSCIENCE, US, vol. 12, no. 12, pages 4878 - 89
See also references of EP 2050446A4
"UROLOGICAL RESEARCH", (USA), vol. 18, no. 5, 1990, pages 349 - 52
"THE JOURNAL OF UROLOGY", (USA), vol. 153, no. 6, June 1995 (1995-06-01), pages 2034 - 8
JOURNAL OF THE JAPANESE UROLOGICAL ASSOCIATION, vol. 92, no. 2, February 2001 (2001-02-01), pages 304
KOBE, THE 89TH ANNUAL MEETING OF THE JAPANESE UROLOGICAL ASSOCIATION, 2001, pages MP-305
"ANESTHESIOLOGY", (USA), vol. 97, no. 5, November 2002 (2002-11-01), pages 1254 - 62
"ANESTHESIA AND ANALGESIA", (USA), vol. 95, no. 6, December 2002 (2002-12-01), pages 1708 - 12
"ANESTHESIA AND ANALGESIA", (USA), vol. 93, no. 4, October 2001 (2001-10-01), pages 1012 - 7
GASTROENTEROLOGY, vol. 124, no. 1, January 2003 (2003-01-01), pages 18 - 25
"Progress in Medicine"", LIFE SCIENCE MEDICAL, vol. 5, 1985, pages 2157 - 2161
"lyakuhin no Kaihatsu", BUNSHI SEKKEI, vol. 7, 1990, pages 163 - 198
"Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS
"Annals of the New York Academy of Science", vol. 51, 1949, pages: 660
THE JOURNAL OF NEUROSCIENCE, US, vol. 12, no. 12, pages 4878 - 89
See also references of EP 2050446A4
Attorney, Agent or Firm:
MORITA, Hiroshi et al. (Intellectual Property 3-11,Nihonbashi-Honcho 2-chom, Chuo-ku Tokyo 11, JP)
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