SULFONAMIDE COMPOUNDS AND USES THEREOF AS MEDICINES

WIPO Patent Application WO/2000/034277

A1

Sulfonamide compounds represented by general formula (I), or salts thereof; and drug compositions containing the same (wherein each symbol is as defined in the description). These compounds serve as preventive or therapeutic agents efficacious against diseases which can be cured through decrease in blood sugar level and those which can be cured through inhibition of cGMP-PDE, relaxation of smooth muscle, bronchodilation, vasodilation, inhibition of smooth muscle fiber, or inhibition of allergy.

KAYAKIRI HIROSHI (JP)
ABE YOSHITO (JP)
HAMASHIMA HITOSHI (JP)
SAWADA HITOSHI (JP)
ISHIBASHI NAOKI (JP)
SETOI HIROYUKI (JP)
OKU TERUO (JP)
YAMASAKI NORITSUGU (JP)
IMOTO TAKAFUMI (JP)
HIRAMURA TAKAHIRO (JP)

PCT/JP1999/006748

June 15, 2000

December 01, 1999

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FUJISAWA PHARMACEUTICAL CO (JP)
KAYAKIRI HIROSHI (JP)
ABE YOSHITO (JP)
HAMASHIMA HITOSHI (JP)
SAWADA HITOSHI (JP)
ISHIBASHI NAOKI (JP)
SETOI HIROYUKI (JP)
OKU TERUO (JP)
YAMASAKI NORITSUGU (JP)
IMOTO TAKAFUMI (JP)
HIRAMURA TAKAHIRO (JP)

A61P43/00; C07D471/04; (IPC1-7): C07D471/04; A61K31/437; A61P43/00; A61P3/06; A61P3/10; A61P9/08; A61P11/08; A61P37/08

WO1999000372A1

1999-01-07

US5215994A

1993-06-01

BEACHAMP H.T. ET AL.: "In vivo receptor occupancy of the angiotensin II recptor by nonpeptide antagonist: relationship to in vitor affinities and in vivo pharmacologic potency", J. PHARMACOL. EXP. THER.,, vol. 272, no. 2, 1995, pages 612 - 618, XP002923630
See also references of EP 1136492A4

Takashima, Hajime (3-9 Hiranomachi 3-chome, Chuo-k, Osaka-shi Osaka, JP)

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