SULFONIC ACID DERIVATIVES OF HYDROXAMIC ACIDS AND THEIR USE AS MEDICINAL PRODUCTS

Title:

SULFONIC ACID DERIVATIVES OF HYDROXAMIC ACIDS AND THEIR USE AS MEDICINAL PRODUCTS

Document Type and Number:

WIPO Patent Application WO/2002/006214

Kind Code:

A1

Abstract:

The invention relates to novel sulfonic acid derivatives of hydroxamic acids or pharmacologically acceptable salts thereof, more specifically, sulfonic acid derivatives of hydroxamic acids useful as lipopolysaccharide (LPS) inhibitors or pharmacologically acceptable salts thereof. Further, the invention also relates to novel intermediates useful in the synthesis of the sulfonic acid derivatives of hydroxamic acids.

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Inventors:

MAEDA KAZUHIRO (JP)
SONDA SHUJI (JP)
TAKEMOTO TADAHIRO (JP)
GOTO TOMOKAZU (JP)
KOBAYASHI FUJIO (JP)
KAJII MASAHIKO (JP)
KOMORITA NARUYASU (JP)
HIRAYAMA FUMIHIRO (JP)

Application Number:

PCT/JP2001/006275

Publication Date:

January 24, 2002

Filing Date:

July 19, 2001

Export Citation:

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Assignee:

WELFIDE CORP (JP)
MAEDA KAZUHIRO (JP)
SONDA SHUJI (JP)
TAKEMOTO TADAHIRO (JP)
GOTO TOMOKAZU (JP)
KOBAYASHI FUJIO (JP)
KAJII MASAHIKO (JP)
KOMORITA NARUYASU (JP)
HIRAYAMA FUMIHIRO (JP)

International Classes:

A61K31/185; A61P29/00; A61P31/04; A61P39/02; A61P43/00; C07C309/11; C07C309/15; C07C309/51; C07D209/48; (IPC1-7): C07C309/11; C07C309/15; C07C309/51; C07D209/48; A61K31/185; A61K31/4035; A61P29/00; A61P31/04; A61P39/02; A61P43/00

Domestic Patent References:

WO1994010990A1

1994-05-26

Foreign References:

EP0832875A1

1998-04-01

Other References: