SULFONYLAMINOCARBONYL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USES THEREOF

Title:

SULFONYLAMINOCARBONYL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/173493

Kind Code:

A1

Abstract:

This disclosure is related to a sulfonylaminocarbonyl derivative of formula (I) and/or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the sulfonylaminocarbonyl derivatives of formula (I) and/or a pharmaceutically acceptable salt thereof, preparation methods thereof, and use thereof in treating FXR and/or TGR5 mediated diseases, including primary biliary cirrhosis, nonalcoholic fatty liver, portal hypertension, bile acid diarrhea and cholestasis, type II diabetes and obesity, etc.

Inventors:

LI QUN (CN)
GAO DAXIN (CN)

Application Number:

PCT/CN2016/080331

Publication Date:

November 03, 2016

Filing Date:

April 27, 2016

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Assignee:

SHANGHAI DE NOVO PHARMATECH CO LTD (CN)

International Classes:

C07J41/00; A61K31/575; A61K31/58; A61P1/00; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P13/12; C07J43/00

Domestic Patent References:

WO2008091540A2	2008-07-31
WO2007095174A2	2007-08-23
WO2008002573A2	2008-01-03

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (SFECO Mansion No.681 Xiaomuqiao Road, Shanghai 2, CN)

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