Title:
SULFONYLUREA DERIVATIVE AND MEDICAL USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/012666
Kind Code:
A1
Abstract:
The present invention relates to a sulfonylurea derivative and medical uses thereof, specifically relating to the sulfonylurea derivative shown in general formula (I), a preparation method thereof, a pharmaceutical composition containing same, and a use of same for treating diseases and disorders affected by neuronal damage, for example: cerebral stroke, brain damage, neuropathic pain, migraines, inflammatory pain, chronic pain, or depression. The definition of each group in general formula (I) is the same as that in the description.
Inventors:
HUANG JIAN (CN)
ZHU LINGJIAN (CN)
YU XIUZHAO (CN)
SUN PIAOYANG (CN)
ZHU LINGJIAN (CN)
YU XIUZHAO (CN)
SUN PIAOYANG (CN)
Application Number:
PCT/CN2021/106746
Publication Date:
January 20, 2022
Filing Date:
July 16, 2021
Export Citation:
Assignee:
SHANGHAI SENHUI MEDICINE CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
International Classes:
C07C311/59; A61K31/64
Domestic Patent References:
| WO2008017925A2 | 2008-02-14 |
Foreign References:
| US7285574B2 | 2007-10-23 | |||
| CN1111238A | 1995-11-08 | |||
| CN103108637A | 2013-05-15 |
Other References:
STEPHONT ROBERT L., NIEDBALA R. SAM, SCHRAYT KEITH J., HEINDEL NED D.: "SYNTHESIS OF 4- trans -[1-[4-[2-(5-CHLORO-2-METHOXYBENZAMIDO)ETHYL] BENZENESULFONYL]UREIDO]CYCLOHEXANOL HEMISUCCINATE ESTER", ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL: THE NEW JOURNAL FOR ORGANIC SYNTHESIS, ORGANIC PREPARATION AND PROCEDURES CO., NEWTON HIGHLANDS, MA., US, vol. 24, no. 3, 1 June 1992 (1992-06-01), US , pages 339 - 342, XP055887457, ISSN: 0030-4948, DOI: 10.1080/00304949209355897
DRUG DES DEVEL THER, vol. 15, 2018, pages 2539 - 2552
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2003, pages 2099 - 2113
See also references of EP 4183774A4
DRUG DES DEVEL THER, vol. 15, 2018, pages 2539 - 2552
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2003, pages 2099 - 2113
See also references of EP 4183774A4
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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