Title:
SUPERCOOLING PROMOTING AGENT
Document Type and Number:
WIPO Patent Application WO/2008/007684
Kind Code:
A1
Abstract:
In the process of investigating a mechanism by which a tree growing in a cold climate maintains cellular water in a liquid state at a low temperature, the inventor conducted an investigation to identify a causative substance of that. As a result, the inventor identified a supercooling promoting substance present in the tree. The supercooling ability of an identified flavonoid glycoside and a synthesized flavonoid glycoside having a similar structure was tested and it was found that a supercooling promoting agent consisting of such a flavonoid glycoside can stably supercool bulk water at a low temperature for a long period of time. An aqueous solution containing the supercooling promoting agent of the present invention is useful as a solution for storing a biological material at a low temperature.
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Inventors:
FUJIKAWA SEIZO
KASUGA JUN
HASHIDOKO YASUYUKI
ARAKAWA KEITA
FUKUSHI YUKIHARU
KASUGA JUN
HASHIDOKO YASUYUKI
ARAKAWA KEITA
FUKUSHI YUKIHARU
Application Number:
PCT/JP2007/063784
Publication Date:
January 17, 2008
Filing Date:
July 11, 2007
Export Citation:
Assignee:
UNIV HOKKAIDO NAT UNIV CORP (JP)
OLYMPUS CORP (JP)
FUJIKAWA SEIZO
KASUGA JUN
HASHIDOKO YASUYUKI
ARAKAWA KEITA
FUKUSHI YUKIHARU
OLYMPUS CORP (JP)
FUJIKAWA SEIZO
KASUGA JUN
HASHIDOKO YASUYUKI
ARAKAWA KEITA
FUKUSHI YUKIHARU
International Classes:
C09K3/00; A01N1/02; C09K5/08; C07H17/07
Domestic Patent References:
WO2004074397A1 | 2004-09-02 | |||
WO1997014785A2 | 1997-04-24 | |||
WO2004074397A1 | 2004-09-02 |
Foreign References:
JPS59109897A | 1984-06-25 | |||
JP2000500327A | 2000-01-18 |
Other References:
KAGAKU TO SEIBUTSU, vol. 43, no. 5, 2005, pages 280 - 282
KAGAKU TO SEIBUTSU, vol. 37, no. 12, 1999, pages 778 - 780
"FLAVONOIDS Chemistry, Biochemistry and Applications", 2006, CRC PRESS TAYLOR AND FRANCIS GROUP
KAGAKU TO SEIBUTSU, vol. 37, no. 12, 1999, pages 778 - 780
"FLAVONOIDS Chemistry, Biochemistry and Applications", 2006, CRC PRESS TAYLOR AND FRANCIS GROUP
Attorney, Agent or Firm:
SHIMODA, Akira et al. (Kyobashi-Nichiei Biru 3-4, Kyobashi 3-chome, Chuo-k, Tokyo 31, JP)
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