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Title:
SUPPOSITORIES SUSTAINED IN THE LOWER RECTUM
Document Type and Number:
WIPO Patent Application WO/2002/024161
Kind Code:
A1
Abstract:
Suppositories sustained in the lower rectum characterized by containing a suppository base which comprises: (A) a fatty acid triglyceride; (B) one or ore glycerol fatty acid esters having 14 to 18 carbon atoms; and (C) a base component sustained in the lower rectum. When held with fingers before inserting into the rectum, these suppositories would not melt due to the body temperature of the fingers and thus can be easily handled. Moreover, they suffer from no deformation due to an increase in temperature during storage and would not irritate the rectal mucosa, thereby causing no congestion, bleeding, enlargement, etc. Namely, these suppositories are highly safe.

Inventors:
HORI SEIICHI (JP)
AIKAWA KATSUYOSHI (JP)
Application Number:
PCT/JP2001/007893
Publication Date:
March 28, 2002
Filing Date:
September 12, 2001
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
HORI SEIICHI (JP)
AIKAWA KATSUYOSHI (JP)
International Classes:
A61K9/00; A61K9/02; A61K31/00; (IPC1-7): A61K9/02; A61K47/12; A61K47/34; A61K31/47; A61K31/245
Foreign References:
JPH04346916A1992-12-02
EP1022019A12000-07-26
EP0848948A11998-06-24
Other References:
See also references of EP 1319397A4
Attorney, Agent or Firm:
Asamura, Kiyoshi (New Ohtemachi Bldg. 2-, Ohtemachi 2-chome Chiyoda-ku Tokyo, JP)
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