Title:
SURFACE-MODIFIED TITANIUM DIOXIDE FINE PARTICLES AND DISPERSION COMPRISING THE SAME, AND METHOD FOR PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/2004/087577
Kind Code:
A1
Abstract:
Surface-modified titanium dioxide fine particles which have a surface chemically modified with a hydrophilic polymer, wherein a carboxyl group of the hydrophilic polymer and titanium dioxide are bound through an ester bonding; and a method for producing the surface-modified titanium dioxide fine particles, which comprises mixing a dispersion comprising titanium dioxide fine particles having a particle size of 2 to 200 nm and a solution of a water-soluble polymer, heating the resultant mixture to a temperature of 80 to 220°C, to thereby bind both the components through an ester bonding, and removing an unbound water-soluble polymer, to purify the resultant particles. The surface -modified titanium dioxide fine particles exhibit excellent dispersibility and stability in an aqueous solvent over a wide pH region including a neutral range.
Inventors:
SONEZAKI SHUJI (JP)
BANZAI TOSHIAKI (JP)
KANEHIRA KOKI (JP)
YAGI SHINICHI (JP)
OGAMI YUMI (JP)
BANZAI TOSHIAKI (JP)
KANEHIRA KOKI (JP)
YAGI SHINICHI (JP)
OGAMI YUMI (JP)
Application Number:
PCT/JP2004/004635
Publication Date:
October 14, 2004
Filing Date:
March 31, 2004
Export Citation:
Assignee:
TOTO LTD (JP)
SONEZAKI SHUJI (JP)
BANZAI TOSHIAKI (JP)
KANEHIRA KOKI (JP)
YAGI SHINICHI (JP)
OGAMI YUMI (JP)
SONEZAKI SHUJI (JP)
BANZAI TOSHIAKI (JP)
KANEHIRA KOKI (JP)
YAGI SHINICHI (JP)
OGAMI YUMI (JP)
International Classes:
A61K33/24; A61K41/00; B01J31/06; B01J35/00; C09C1/36; C02F1/30; C02F1/32; (IPC1-7): C01G23/047; A61K33/00; A61K41/00; A61K47/48; A61K47/02; B01J35/02
Foreign References:
JPH1067516A | 1998-03-10 | |||
JP2002316946A | 2002-10-31 | |||
JP2002316950A | 2002-10-31 | |||
JP2002316946A | 2002-10-31 | |||
JP2002316950A | 2002-10-31 |
Other References:
R. CAI ET AL., CANCER RESEARCH, vol. 52, 1992, pages 2346 - 2348
FX PERRIN, POLYM INT, vol. 51, 2002, pages 1013 - 1022
See also references of EP 1630136A4
FX PERRIN, POLYM INT, vol. 51, 2002, pages 1013 - 1022
See also references of EP 1630136A4
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