Title:
SYNTHESIS OF CERIA-ZIRCONIA SOLID SOLUTION NANOPARTICLES AND CERIA-ZIRCONIA NANOCOMPOSITE, AND APPLICATION THEREOF AS SEPSIS THERAPEUTIC AGENT
Document Type and Number:
WIPO Patent Application WO/2018/235976
Kind Code:
A1
Abstract:
The present invention relates to a ceria-zirconia nanocomposite, a pharmaceutical composition containing the same, and a preparation method therefor. More specifically, the present invention provides: a ceria-zirconia nanocomposite having a structure in which a surfactant encompasses ceria-zirconia solid solution nanoparticles; an antioxidant and a sepsis therapeutic agent which contain the same; and a preparation method therefor.
Inventors:
HYEON TAEG HWAN (KR)
LEE SEUNG HOON (KR)
SOH MIN (KR)
KIM CHI KYUNG (KR)
LEE SEUNG HOON (KR)
SOH MIN (KR)
KIM CHI KYUNG (KR)
Application Number:
PCT/KR2017/006617
Publication Date:
December 27, 2018
Filing Date:
June 22, 2017
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
INST BASIC SCIENCE (KR)
SEOUL NAT UNIV HOSPITAL (KR)
INST BASIC SCIENCE (KR)
SEOUL NAT UNIV HOSPITAL (KR)
International Classes:
A61K9/51; A61K33/00; A61K47/50
Foreign References:
| KR101696903B1 | 2017-01-17 | |||
| KR20130114469A | 2013-10-17 | |||
| US8795731B1 | 2014-08-05 | |||
| KR101770414B1 | 2017-09-29 |
Other References:
SHARMA, R. ET AL.: "Preparation and Characterization of Surfactant Coated Ce-Zr Nanoparticles and Nanofuel", JOURNAL OF ASTM INTERNATIONAL, vol. 9, no. 5, May 2012 (2012-05-01), pages 1 - 11, XP055559470
KANG, D.-W. ET AL.: "Anti-inflammatory Effects of Ceria-Zirconia Nanoparticles for Stroke Treatment", 2015 KOREAN STROKE SOCIETY SPRING CONFERENCE , ORAL PRESENTATION, 9 May 2015 (2015-05-09), The-K Hotel, Seoul, Korea
LI, G. ET AL.: "Effect of Iron Doping into CeO2-ZrO2 on the Properties and Catalytic Behaviour of Pd-only Three-way Catalyst for Automotive Emission Control", JOURNAL OF HAZARDOUS MATERIALS, vol. 186, no. 1, 2011, pages 911 - 920, XP028140253
KIM, C. K. ET AL.: "Ceria Nanoparticles that Can Protect against Ischemic Stroke", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 51, no. 44, 2012, pages 11039 - 11043, XP055559495
KANG, D.-W. ET AL.: "Anti-inflammatory Effects of Ceria-Zirconia Nanoparticles for Stroke Treatment", 2015 KOREAN STROKE SOCIETY SPRING CONFERENCE , ORAL PRESENTATION, 9 May 2015 (2015-05-09), The-K Hotel, Seoul, Korea
LI, G. ET AL.: "Effect of Iron Doping into CeO2-ZrO2 on the Properties and Catalytic Behaviour of Pd-only Three-way Catalyst for Automotive Emission Control", JOURNAL OF HAZARDOUS MATERIALS, vol. 186, no. 1, 2011, pages 911 - 920, XP028140253
KIM, C. K. ET AL.: "Ceria Nanoparticles that Can Protect against Ischemic Stroke", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 51, no. 44, 2012, pages 11039 - 11043, XP055559495
Attorney, Agent or Firm:
HAN, Sang Soo (KR)
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