Title:
SYNTHESIS OF GLYCOPEPTIDES WITH SUPERIOR PHARMACOKINETIC PROPERTIES
Document Type and Number:
WIPO Patent Application WO2005044197
Kind Code:
A3
Abstract:
The present invention relates to novel glycopeptides having improved pharmacokinetic properties, improved stability, methods of preparing said novel glycopeptides, and methods to use said novel glycopeptides.
Inventors:
DUFFIELD JONATHAN (US)
MARBY KENNETH (US)
O'HARE SEAN (US)
HWANG CHAN-KOU (US)
ICHIKAWA YOSHITAKA (US)
MARBY KENNETH (US)
O'HARE SEAN (US)
HWANG CHAN-KOU (US)
ICHIKAWA YOSHITAKA (US)
Application Number:
PCT/US2004/036551
Publication Date:
August 18, 2005
Filing Date:
November 01, 2004
Export Citation:
Assignee:
OPTIMER PHARMACEUTICALS INC (US)
DUFFIELD JONATHAN (US)
MARBY KENNETH (US)
O'HARE SEAN (US)
HWANG CHAN-KOU (US)
ICHIKAWA YOSHITAKA (US)
DUFFIELD JONATHAN (US)
MARBY KENNETH (US)
O'HARE SEAN (US)
HWANG CHAN-KOU (US)
ICHIKAWA YOSHITAKA (US)
International Classes:
A61K38/14; A61K38/16; C07K9/00; C07K14/00; A61K; (IPC1-7): A61K38/14; A61K38/16; C07K9/00; C07K14/00
Foreign References:
| US5212298A | 1993-05-18 | |||
| US5262312A | 1993-11-16 | |||
| US20030153492A1 | 2003-08-14 | |||
| US20030158093A1 | 2003-08-21 |
Other References:
PALIAN M.M. ET AL.: "Glycopeptide-membrane interactions: glycosyl enkephalin analoges adopt turn conformations by NMR and CD in amphipathic media.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 125, no. 19, 22 April 2003 (2003-04-22), pages 5823 - 5831, XP002983424
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