The present invention concerns a syringe holder. More precisely, the present invention concerns a syringe holder capable of allowing fine control of the injection of products, in particular products for aesthetic medicine, such as filler products or botulinum toxin.

As is known, the syringes currently on the market, in their more or less ergonomic forms, represent the most commonly used instrument for injecting fluids into tissues in any anatomical district.

This tool, although it offers the operator sufficient handling conditions, does not allow the amount of injected material to be finely adjusted.

In fact, the syringes of the known art usually comprise - a cylinder (container) wherein the liquid to be injected is inserted,

- a needle, arranged at one end of the cylinder and in fluidic connection with the inside of the cylinder, to allow the perforation of the tissue at the injection point and the subsequent emission of liquid to be injected through it,

- a piston, sliding inside the cylinder, in order to exert sufficient pressure for the movement and the emission of the liquid to be injected by sliding the piston inside the cylinder, and

- a stem, coupled to the piston and controllable by the operator to move the piston.

In particular, in the syringes of the known art, the movement of the fluid in the cylinder is proportional to the viscosity of the fluid itself, to the gauge of the needle and to the length of the needle, to the resistance of the tissues where the inoculation is made, to the properties of penetration and/or imbibition of the fluid (they too depending on the viscosity of the fluid itself).

Specifically, the resistance to inoculation exerted on the fluid to be injected depends on the following parameters: - the elastic modulus E o the fluid to be injected: indicates the capacity of the filler to return to its original form when subjected to dynamic forces: the greater the elastic modulus, the “harder and more compact” the fluid will be to be injected;

- the viscosity m of the fluid to be injected, i.e. the resistance of the fluid to the dynamic flow forces;

- the tan d ratio, i.e. the ratio between the elastic modulus f and the viscosity m

- parameters relating to the means of inoculation, such as the gauge of the needles or cannulas used; and

- tissue resistance, which depends on the consistency of the anatomical and cellular structure wherein the fluid must be injected, and determines the differences in penetrability to the needle and fluid.

In this regard, it is good to remember that the resistance to fluid inoculation rarely is null: on the contrary, when this occurs it indicates the danger of the move, as it can indicate the presence and infibulation of a vessel, the presence and invasion of a cavity, etc.

The inoculation of the fluid takes place through manual control by the operator, who, after having pierced the tissue with the needle, pushes on the piston to allow the passage of fluid from the cylinder to the tissue itself.

However, the inoculation methodology just described does not allow a precise control of the amount of material injected, and is often neither ergonomic nor instinctive. In fact, the syringe is usually gripped with the index and middle fingers in correspondence of the cylinder, while the stem, which pushes the piston inside the cylinder, is handled by the thumb or palm of the hand, usually in correspondence of the hypothenar eminence.

As it can be well understood, the thrust control of the stem is not perceptible by the thumb or the thenar eminence (wherein by thenar eminence or “thenar” it is meant the fleshy relief placed at the base of the thumb on the palmar face of the hand), because the micrometric control, as necessary for fillers and botulinum toxin, depends on the viscosity parameters of the fluid and its resistance to movement. It is also necessary to consider the distance of the injection site from the control system: in fact, this is not represented by the finger (index and middle fingers) - needle gap, but by the section that goes from the end of the stem in contact with the thumb (or palm) to the needle.

In addition, in the case of products for aesthetic medicine, a safety suction is carried out before inoculation, to check that no blood vessels or other hollow organs have been perforated.

In fact, the possible injection of fillers or botulinum toxin inside blood vessels is linked to various medical complications, such as the onset of thrombus.

The suction consists in moving the syringe stem back, when the needle is inserted into the tissue, so as to create a decrease in pressure inside the syringe, due to an increase in the volume of the chamber, which allows, by mere physical principle, the possible suction of blood.

In applications related to aesthetic medicine, one of the difficulties is that the suction step must be repeated several times, since the fluid is injected several times and in different quantities in different injection points.

To overcome, at least partially, such limitations in the inoculation of fluids by syringe, some solutions have been proposed for the administration of anesthetics in the dental field, such as the Sopira Citoject® by Kulzer® or the peripress syringe or the Dentapen® syringe holder by Juva®.

However, such systems of the known art only allow the injection of material into the tissue, but not to perform the safety suction.

Recently, electronically controlled syringe holders have been proposed, such as the Dermapen®, Lipopen®, Juvapen®, or Teosyalpen® systems, for inoculations in aesthetic medicine, which allow to inoculate a fluid (filler - botulinum toxin) with a predetermined pressure.

However, such solutions require that the stem be removed from the syringe to be inserted into the syringe holder and do not in any way allow the transmission of the flow sensitivity to the operator, because the pressure is electronically predetermined by the machine through quantity and/or resistance parameters predefined by the operator himself before injection. This deprives the operator of the sensitivity to fluid flow.

This involves

- poor ergonomics, as the index finger - middle finger - hypothenary eminence system must be used similarly to the syringes of the known art;

- poor accuracy of use in the site and in the handling of the syringe and needle; and

- poor easiness of loading and use (modification of the syringe supplied: removal of the plunger and handle).

The aim of the present invention is to overcome the drawbacks of the known art.

In particular, an aim of the present invention is to provide a syringe holder that allows to perform the injection of liquids in a controlled manner, allowing to vary the pressure exerted on the fluid (injection force) during the injection on the basis of the resistance exerted on the fluid itself.

Furthermore, an aim of the present invention is to provide a syringe holder that allows to perform an injection in a precise manner, without the possibility of moving the syringe during its use.

In addition, an aim of the present invention is that such syringe holder allows to perform the safety suction.

A further aim of the present invention is that such syringe holder is simple to use and allows its use with a plurality of syringes on the market.

Still another aim of the present invention is that such syringe holder is easy to manufacture and has low production costs.

Finally, the aim of the present invention is that such syringe holder has an ergonomic handle, which facilitates the inoculation operations for the operator, being easily operable.

The object of the present invention is therefore a syringe holder for a syringe, wherein said syringe comprises a hollow body containing a fluid to be injected, a piston, slidingly and internally coupled to the body along an axis, and a stem coupled to the piston and comprising an end portion for pushing the piston into said body, by sliding along a first direction of said sliding axis, for the consequent release of said fluid into the tissue of a patient, said syringe holder comprising a casing which defines a housing for housing at least one portion of the body of a syringe parallel to said sliding axis; a first sliding member, slidingly coupled to said casing with freedom of sliding parallel to said sliding axis; a second sliding member, slidingly coupled to said casing with freedom of sliding parallel to said sliding axis; a first coupling device integrally coupled to said first sliding member and to said second sliding member and which can be coupled to the stem of said syringe; first locking and releasing means which can be coupled to said first sliding member and second locking and releasing means which can be coupled to said second sliding member, in such a way that, in use, by acting on said first locking and releasing means, these pass from a first configuration, wherein they do not interact with said first sliding member, to a second configuration, wherein they are coupled to said first sliding member in such a way as to induce the sliding thereof along said first direction and block the sliding along a second direction opposite to said first direction, so as to push said piston into said syringe body; and by acting on said second locking and releasing means, these pass from a first configuration, wherein they do not interact with said second sliding member, to a second configuration, wherein they are coupled with said second sliding member in such a way as to induce the sliding thereof along said second direction and prevent it from sliding along said first direction so as to make said piston move away from said syringe body, so as to generate a suction force in said body.

An object of the present invention is also a syringe holder for a syringe, wherein said syringe comprises a hollow body containing a fluid to be injected, a piston, slidingly and internally coupled to the body along an axis, and a stem coupled to the piston and comprising an end portion for pushing the piston into said body, by sliding along a first direction of said sliding axis, for the consequent release of said fluid into the tissue of a patient, said syringe holder comprising a casing which defines a housing for housing at least one portion of the body of a syringe parallel to said sliding axis; a first sliding member, slidingly coupled to said casing with freedom of sliding parallel to a sliding axis; a second sliding member, slidingly coupled to said casing with freedom of sliding parallel to said sliding axis; a first coupling device integrally coupled to said first sliding member and to said second sliding member and which can be coupled to the stem of said syringe in such a way that the sliding axis of the syringe is parallel to the sliding axis of said first and second sliding members; first locking and releasing means which can be coupled to said first sliding member and second locking and releasing means which can be coupled to said second sliding member, in such a way that, in use, when said first coupling device is coupled to the stem of said syringe, by manually acting on said first locking and releasing means, these pass from a first configuration, wherein they do not interact with said first sliding member, to a second configuration, wherein they are coupled to said first sliding member in such a way as to induce the sliding thereof along said first direction and block the sliding along a second direction opposite to said first direction, so as to push said piston into said syringe body; and by manually acting on said second locking and releasing means, these pass from a first configuration, wherein they do not interact with said second sliding member, to a second configuration, wherein they are coupled with said second sliding member in such a way as to induce the sliding thereof along said second direction and prevent its sliding along said first direction so as to make said piston move away from said body of the syringe, so as to generate a suction force in said body.

Furthermore, according to the invention, the coupling between said first locking and releasing means with said first sliding member can take place by means of a ratchet mechanism and the coupling between said second locking and releasing means with said second sliding member can take place via a ratchet mechanism.

In particular, according to the invention, said first sliding member can be a first rack comprising a plurality of teeth and said first locking and releasing means can comprise a first lever coupled to said body with freedom of rotation, a first pawl coupled to said first lever with freedom of rotation, and first elastic return means coupled to said first lever and said first pawl in such a way that, by pushing on said first lever, said first locking and releasing means pass from said first configuration to said second configuration, wherein in said first configuration, said first pawl does not interact with said first rack, and in said second configuration, said first pawl interacts with a tooth of said first rack under the action of said first elastic return means, so that a thrust force in said first direction is exerted on said first rack.

More in particular, according to the invention, said first elastic return means can comprise a first spring coupled to said first lever and said casing and a second spring coupled to said first pawl and said first lever.

Still according to the invention, said second sliding member can be a second rack comprising a plurality of teeth, said second locking and releasing means can comprise a second lever arranged on a carriage slidingly coupled to said casing along said sliding axis, a second pawl arranged on said carriage, coupled with freedom of rotation to said second lever, and second elastic return means, so that, by pushing on said carriage and on said second lever, said second locking and releasing means pass from said first configuration to said second configuration, wherein in said first configuration, said second pawl does not interact with said second rack, in said second configuration, said second pawl interacts with a tooth of said second rack under the action of said second elastic return means so that a thrust force in said second direction is exerted on said second rack.

Always according to the invention, said second elastic return means can comprise a third spring coupled to said second lever and said carriage, and a fourth horizontal spring arranged between said carriage and said casing and said second locking and releasing means can comprise a connecting rod for said coupling with freedom of rotation between said second lever and said second pawl.

Further according to the invention, said first sliding member and said second sliding member can be arranged on two opposite portions of said casing relative to said sliding axis.

Preferably according to the invention, said syringe holder can comprise a second coupling device inserted into a portion of said housing of said casing and sliding along said sliding axis, said second coupling device can be coupled to said body of said syringe for locking it in place in said housing.

In particular, according to the invention, said second coupling device can comprise a ring and at least one elastic gripping portion coupled to said ring to allow the insertion of said syringe into said syringe holder and said casing can comprise a first projection having a substantially annular shape, comprising a flat wall and an inclined wall, and a second projection spaced from said first projection, said ring being arranged between said first projection and said second projection and said elastic gripping portion being arranged in abutment against said inclined wall.

More in particular, according to the invention, said second coupling device can comprise a plurality of elastic gripping portions evenly arranged on said ring.

Furthermore, according to the invention, said first coupling device can comprise a slot for said stem of said syringe and clamping means able to be closed on said slot for clamping said stem in said slot.

Still according to the invention, said coupling device may comprise a first tooth for coupling with an indentation of said first rack and a second tooth for coupling with an indentation of said second rack.

Always according to the invention, said first lever can be arranged at an upper portion of said casing and said second lever can be arranged at a lower portion of said casing.

Furthermore, an object of the present invention is an assembly, comprising a syringe holder as described and a syringe comprising a hollow body for containing a fluid to be injected, a piston, slidingly and internally coupled to the body along said axis, and a stem coupled to the piston and comprising an end portion, for pushing the piston into said body.

In particular, according to the invention, said syringe body can contain said fluid to be injected, said fluid to be injected being a fluid for cosmetic treatments of aesthetic medicine, in particular being a filler product or a fluid containing botulinum toxin.

Finally, the cosmetic use of the described assembly is an object of the present invention. The invention will now be described for illustrative but not limitative purposes, with particular reference to the drawings of the attached figures, where:

Figure 1 shows a perspective view of a first embodiment of a syringe holder according to the present invention inside which a first syringe of a first length is inserted, the stem of the first syringe is coupled to a first coupling device of the syringe holder and wherein the body of the first syringe is coupled to a second coupling device of the syringe holder, and wherein the syringe holder comprises a metering lever, which controls the movement of the first coupling device and a suction trigger, to allow suction before injection;

Figure 2 shows a side view of the syringe holder of Figure 1 , wherein some internal components can be seen in transparency;

Figure 3 shows a detail of Figure 2;

Figure 4 shows a perspective view of the second coupling device of the syringe holder of Figure 1 in an open configuration;

Figure 5 shows a perspective view of the second coupling device of Figure 4 in an intermediate configuration;

Figure 6 shows a perspective view of the second coupling device of Figure 4 in a closed configuration;

Figure 7 shows a perspective view of a side section of a detail of the syringe holder of Figure 1 , wherein the body of the first syringe coupled to the second coupling device and the stem of the first syringe coupled to the first coupling device can be seen;

Figure 8 shows a perspective view of a detail of the syringe holder of Figure 1 , wherein the stem of the first syringe coupled to the first coupling device is shown;

Figure 9 shows a perspective view of the first coupling device of the syringe holder of Figure 1 in an open configuration;

Figure 10 shows a perspective view of the first coupling device of the syringe holder of Figure 1 in a closed configuration;

Figure 11 shows a perspective view of the syringe holder of Figure 1 in a first step of inserting the first syringe, wherein the first syringe is not yet coupled with the first coupling device nor with the second coupling device;

Figure 12 shows a perspective view of the syringe holder of Figure 1 in a second step of inserting the first syringe, wherein the first syringe is coupled with the second coupling device but not with the first coupling device;

Figure 13 shows a perspective view of the syringe holder of Figure 1 , inside which a second syringe of a second length, shorter than said first length, is inserted;

Figure 14 shows a perspective view of a detail of Figure 13, wherein the stem of the second syringe coupled to the first coupling device can be seen in transparency;

Figure 15 shows a schematic side view of a third embodiment of a syringe holder according to the present invention coupled to a syringe in a rest position, wherein the syringe is full, with the piston completely outside the body the syringe, with the suction trigger in a rest configuration;

Figure 16 shows a schematic side view of the syringe holder of Figure 15 in an intermediate position, wherein the piston is partially arranged inside the body of the syringe and wherein the suction trigger is in an operating configuration;

Figure 17 shows a schematic side view of the syringe holder of Figure 15 in a final position, wherein the piston is arranged completely inside the syringe body, which has been emptied of its contents, and wherein the suction trigger is back to its rest configuration;

Figure 18 shows a schematic side view of a syringe holder according to the present invention, coupled to a syringe in a rest position, wherein the syringe is full, wherein the metering lever is completely raised and consequently the syringe piston is arranged completely outside the syringe body; and

Figure 19 shows a schematic side view of the syringe holder of Figure 18 in an intermediate position, wherein the metering lever is partially lowered and consequently the syringe piston approaches the syringe body.

Referring in particular to Figures 1 - 14, a syringe holder 1 according to the invention is now described in a first embodiment. Said syringe holder 1 is adapted to control the injection of fluids by means of a syringe 100.

In particular, the syringe holder 1 can be used with a syringe 100 comprising a hollow body 101 or cylinder, inside which the fluid to be injected is contained, a piston 102, arranged at least partially inside the body 101 and slidingly coupled thereto along a longitudinal X axis, and a stem 103, coupled to the piston 102 at a first end of the body 101 to control the movement of the piston 102 inside the body 101 along said longitudinal X axis. In particular, the stem 103 comprises an end portion 1030, in particular external to the body 101. This end portion 1030 generally has a larger diameter than the stem 103.

The syringe 100 also comprises a needle 104, coupled to the second end of the body 101 , to allow the penetration and injection of the fluid into a tissue.

The body 101 of the syringe 100 has a substantially cylindrical shape whose axis of symmetry is arranged along the longitudinal X axis. Therefore, when said piston 102 is pushed towards the inside of the body 101 , sliding along a first direction x1 of the longitudinal X axis, the fluid contained in the body 101 is pushed outwards, since the free volume inside the body 101 decreases, with a consequent increase in the pressure exerted on the fluid. On the contrary, if the piston 102 is pushed along a second direction x2 of the X axis opposite to the first direction x1 , the pressure inside the body 101 decreases as the free volume inside the body 101 increases, generating a possible suction force, which allows for example to perform the safety suction.

A syringe 100 which can be coupled to the syringe holder 1 can have variable dimensions, for example a diameter between 8 mm and 10 mm and a length between 108 mm and 156 mm. In the first embodiment of the syringe holder according to the invention shown in Figures 1 - 12, the syringe 100 has a first length equal to about 156 mm, while in Figures 13 and 14 it is shown the same syringe holder 1 coupled to a syringe 100 having a second length, equal to about 108 mm.

The syringe holder 1 comprises a casing 2 defining a housing 20 for housing at least one portion of the body 101 of a syringe 100.

In the embodiment of Figure 1 , such casing 2 has a substantially cylindrical shape whose X axis coincides with the longitudinal X axis of the syringe 1 , when it is housed in said housing 20. Furthermore, the casing 20 has an elliptical section. The casing 2 includes a rear end 200, at which the stem 103 of the syringe 100 will be arranged, and a front end 201 , at which the tip of the syringe 100 will be arranged.

The front end 201 has a troncoconical shape, itself too with an elliptical section, and including a central hole 21 .

The choice of the elliptical section allows to optimise the space inside the housing 20 for the insertion of the elements inside the syringe holder 1 , such as racks 3 and 8 and related guides, better illustrated below. This also allows to obtain a more compact and ergonomic shape than the circular one. Flowever, in further embodiments (not shown), the front part of the syringe holder 1 can undergo further changes in shape to favor a better grip and use of the device.

Thanks to the particular shape of the syringe holder, the insertion of the syringe 100 into the body of a patient to be treated is facilitated.

In fact, a syringe 100 loaded with fluid can be inserted inside the syringe holder 1 without a needle 104, which is subsequently mounted from the outside, being inserted through the central hole 21.

The troncoconical shape of the end of the casing 2 ensures the correct positioning of the syringe 100 relative to the central hole 21.

Therefore, when the syringe 100 is in position inside the syringe holder 1 , the needle 104 protrudes from said casing 2, while the body 101, the piston 102 and the corresponding plunger 103 are arranged inside the housing 20.

Furthermore, in correspondence of the housing 20, the casing 2 comprises a first portion 22, or upper portion 22, comprising a first track 220 (visible in Figure 7). The casing 2 also comprises a second portion 23, or lower portion 23, opposite to the first portion 22, and comprising a second track 230. In particular, in the embodiment shown, the upper portion 22 and the lower portion 23 are arranged along the major axis of the elliptical section of the casing 2.

A first shaped projection 24’ (shown in Figure 7) protrudes from the internal wall of said housing 20, to lock in position a coupling device 4, better illustrated below. Such first projection 24’ is arranged downstream of the tracks 220, 230, with reference to a first direction X1 , which goes from said rear end 200 to said front end 201 of the casing 2. This first direction X1 is therefore coincident with the first direction X1 of the syringe 100.

In the example shown in the figures, the first projection 24’ has a substantially annular shape whose section has a substantially right-angled triangle shape.

In particular, a cathetus (or flat side) of said right-angled triangle forms a flat wall 240 along a direction transverse to said longitudinal X axis and faces the rear end 200 of the casing 2. Instead, the hypotenuse (or inclined side) connects with the inner wall of the housing 20 towards said front end 201 and therefore forms an inclined wall 240 inside said housing 20. In this way, said first projection 24’ allows to form a troncoconical shaped cavity inside said housing 20.

A second projection 24” of substantially annular shape is arranged between said tracks and said first projection 24’ and is spaced from the first projection 24’, for the reasons illustrated below.

Finally, the casing 2 has side openings 25, to allow the view of the contents of the body 101 of the syringe 100. Glasses can be installed on said side openings 25.

The syringe holder 1 also comprises, a first sliding member 3, in particular a first rack 3, or upper rack 3, coupled to the casing 2 with freedom of sliding along the X axis.

In particular, the first rack 3 is slidingly coupled to the first track 220 of the casing 2. In particular, between the first rack 3 and the casing 2 there is a prismatic coupling. The first rack 3 comprises a plurality of teeth 30. Each tooth 30 is spaced from the next tooth 30 by a distance of about 3 mm, so as to ensure a fine control during the injection of a fluid, as better illustrated below. Each tooth 30 has a sawtooth shape comprising a flat side, perpendicular to said longitudinal X axis and facing said rear end 200, and an inclined side.

The syringe holder 1 also comprises first locking and releasing means 6 coupled to the casing 2 and adapted to interact with said first rack 3. In particular, the coupling between said first locking and releasing means 6 with said first sliding member 3 takes place via a ratchet mechanism.

In particular, said first locking and releasing means 6 are configured to pass from a first configuration, wherein they do not interact with the first rack 3 to a second configuration, wherein they interact with the first rack 3 in such a way as to induce the sliding thereof along a first direction X1 and block the sliding thereof along a second direction X2 on an axis parallel to said longitudinal X axis. In particular, the first direction X1 is parallel and concordant with said first direction x1 of the piston 102 and said second direction X2 is parallel and concordant with said second direction x2 of the piston.

Furthermore, the syringe holder 1 comprises a first lever 7, or metering lever 7, which can be operated from the outside, coupled to the outer wall of the casing 2 and associated with said first locking and releasing means 6 to control them.

The first lever 7 is arranged on the casing 2 in such a way as to perform a rotational movement in an anticlockwise direction, when the syringe holder 1 is used. Such movement facilitates the user, as it allows to pick up the syringe holder 1 as if it were a pen and to rotate the lever 7 simply by manually pressing with the index finger.

In particular, the first locking and releasing means 6 comprise a first pawl 60 coupled to the first lever 7 with freedom of rotation and first elastic return means 61. In this way, by pushing on the first lever 7, said first locking and releasing means 6 pass from the first configuration, wherein the first pawl 60 does not interact with the first rack 3, to the second configuration, wherein the first pawl 60 interacts with a tooth 30 of the first rack 3 under the action of the first elastic return means 61.

Therefore, the first lever 7 - first pawl 60 - first rack 3 system behave like a rocker arm - connecting rod - piston kinematic mechanism and by pressing with the index finger on the first lever 7 in anticlockwise direction downwards, the rotation of the first lever 7 itself is determined and, by means of the first pawl 60, the advancement of the first rack 3 is generated.

Therefore, by pushing on the first lever 7 it is possible to exert a thrust force to favor the sliding of the first rack 3 in the first direction X1 , as better illustrated below. This allows the injection of a fluid contained in a syringe 100 by pressing only with the index finger, while the syringe holder

1 is gripped as if it were a pen.

Observing in particular Figure 7, the first elastic return means 61 comprise a first spring 610 arranged between the first lever 7 and the casing

2 and a second spring 611 arranged between the first pawl 60 and the first lever 7, whose operation will be better illustrated below.

The syringe holder 1 also includes a second sliding member 8, in particular a second rack 8, or lower rack 8, coupled to the casing 2 with freedom of sliding along the X axis.

The second rack 8 is slidingly coupled to the second track 230 of the casing 2 (prismatic type coupling).

Therefore, the first rack 3 and the second rack 8 are arranged facing each other relative to the housing of the casing 2.

Also the second rack 8 comprises a plurality of teeth 80. Each tooth 80 is spaced from the next tooth 80 by a distance of approximately 3 mm.

Each tooth 80 has a saw-tooth shape comprising a flat side, perpendicular to said first direction X1 and facing said front end 201 of the body 2. In other words, the first rack 3 and the second rack 8 have teeth 30, 80 oriented in opposite directions.

So, the two racks 3 and 8 are identical and integral with each other, but reversed to each other, as they are equipped with opposite teeth 30, 80.

As can be seen in Figure 2, the syringe holder 1 also comprises second locking and releasing means 9 configured to pass from a first configuration, wherein they do not interact with the second rack 8, to a second configuration, wherein they interact with the second rack 8 in such a way as to induce the sliding thereof along said second direction X2 and prevent the sliding thereof along said first direction X1. Also in this case where the coupling between said second locking and releasing means 9 and said second sliding member 8 occurs through a ratchet mechanism.

The syringe holder 1 also includes a second lever 10, or trigger 10, also called suction trigger 10, at the outer wall of the casing 2 and can be operated from the outside. Said trigger 10 is associated with the second locking and releasing means 9 to control them.

The trigger 10 is configured to rotate in an anticlockwise direction and/or translate in said second direction X2, when the syringe holder 1 is used, as better illustrated below, to operate the second locking and releasing means 9.

In particular, the syringe holder 1 comprises a carriage 11 , also called trigger guard 11 , coupled with freedom of sliding to the casing 2, and comprising a first protrusion 110. Such carriage 11 is inserted on the casing 2 in the longitudinal direction from the front and bottom part. After assembly, the carriage 11 remains in a limited stroke area for the subsequent slightly forced insertion of a front cap 111 , which limits its movements.

The trigger 10 is coupled to the carriage 11 with freedom of rotation, being arranged on the first protrusion 110.

The protrusion 110 is configured in such a way as not to hinder the sliding of the second rack 8 relative to the casing 2.

As shown in particular in Figure 2, the second locking and releasing means 9 comprise a second pawl 90 coupled with freedom of rotation to the carriage 11 and to the trigger 10.

In one embodiment, the carriage 11 may comprise a second protrusion for the second pawl 90.

In particular, the trigger 10 and the second pawl 90 are coupled with a turning coupling by means of a connecting rod 92.

The syringe holder 1 further comprises second elastic return means 91 , configured in such a way that, by manually pushing on the trigger 10 and/or on the carriage 11 , the second locking and releasing means 9 pass from the first configuration, wherein the second pawl 90 does not interact with the second rack 8, to the second configuration, wherein the second pawl 90 interacts with a tooth 80 of the second rack 8 under the action of the second elastic return means 91.

In other words, by pushing on the trigger 10 and/or on the carriage 11 it is possible to exert a thrust force to favor the sliding of the second rack 8 in the second direction X2, for the reasons illustrated below.

The second elastic return means 91 comprise a third spring 910 arranged between the trigger 10 and the carriage 11 and a fourth spring 911 arranged between the carriage 11 and the casing 2. In the exemplary embodiment shown in Figures 1 - 12, the fourth spring 911 is a horizontal spring 911.

Furthermore, the syringe holder 1 shown in Figures 1 - 12 comprises a first coupling device 5, or locking mechanism 5, configured to couple integrally with the two racks 3 and 8 and with the stem 103 of the syringe 100, once positioned inside the casing 2. More particularly, in use, when said first coupling device 5 is coupled to the stem 103 of said syringe 100, the sliding X axis of the syringe 100 is parallel to the sliding X axis of said first and second sliding members 3 and 8. Therefore, the stem 103 of the syringe 100, the sliding means 3, 8 and the coupling means 5 are integrally coupled with each other and are able to slide parallel to the sliding X axis.

With particular reference to Figures 7 - 10, the locking mechanism 5 comprises a slot 50 where inserting the stem 103 of the syringe 100 and clamping means 51 , in particular movable clips 51 , to clamp the stem 103, once it has been positioned in the slot 50. In particular, these clamping means 51 are adapted to clamp the end portion 1030 of the stem 103 of the syringe.

The clips 51 are preferably metal clips, to ensure the correct clamping of the stem 103.

Preferably, the locking mechanism 5 is configured in such a way that, in use, the clips 51 are positioned along the minor axis of the elliptical section of the casing. Along the major axis, there is in fact the coupling with the first rack 3 and with the second rack 8, so there could not be enough space to install the clips in such way.

Furthermore, the locking mechanism 5 includes a first tooth 52 for coupling with the track 220 of the first rack 3 and a second tooth 53 for coupling with the track 230 of the second rack 8 (shown in Figure 7).

Such indentations are arranged on the side opposite to the respective teeth 30, 80 of the racks 3, 8.

Advantageously, in such way, it is possible to adjust the position of the locking mechanism 5 relative to the casing 2, so that the syringe holder 1 can be used with syringes 100 of different lengths, as shown respectively in Figures 1 - 12 and 13 - 14.

In fact, the teeth 52, 53 of the locking mechanism 5 can be inserted into the tracks 220 and 230 of the respective racks 3, 8 starting from the rear end 200 of the syringe holder 2 and manually pushed until they touch, with the open clips 51 , the terminal portion 1030 of the stem 103 of the loaded syringe 100, which is already locked in abutment against the front end 201. Such loaded syringe 100 can therefore have different lengths and diameters.

Therefore, the locking mechanism 5 and the two racks 3 and 8, when coupled together, form a fork or loader for the syringe 100 and the two racks 3 and 8 are rigidly coupled to each other.

Finally, the syringe holder 1 shown in Figures 1 - 12 comprises a second coupling device 4, or locking “gripper” 4 or pincer element 4, for coupling with the body 101 of the syringe 100, so as to hold it in place when in use.

In particular, the pincer element 4, shown in detail in Figures 4 - 6, comprises a ring 40, or rear joint 40, and three elastic gripping portions 41 , or “elastic fingers” 41 , fixed on the ring 40, to allow the insertion of the syringe 100 into the hole of the ring 40 and its stable grip by the three gripping portions 41.

In fact, the elastic fingers 41 are made in such a way as to be able to pass from an open configuration (shown in Figure 4) to a semi-open (shown in Figure 5) or closed (shown in Figure 6) configuration, if stressed by a force of radial compression.

The pincer element 4 is arranged inside the housing 20 with the ring 40 arranged between said first projection 24’ and said second projection 24” and said elastic fingers 41 arranged in abutment against the inclined wall 241 of the first projection 24’.

In such way, inside the housing 20 of the casing 2 of the syringe holder 1 , the closure of the three elastic fingers 41 occurs by wedge effect, similarly to the closure of a classic mechanical pencil.

In particular, in the embodiment shown in Figures 1 - 7, the pincer element 4 provides for a pushing helical spring 42 (shown in Figures 2, 3 and 7), which is interposed and abuts against the flat side 240 of the first projection 24’ and with the ring 40.

The second projection 24” prevents the pincer element 4 from exiting the troncoconical shaped cavity by sliding towards said rear end 200.

Therefore, when the helical spring 42 is extended, it distances the ring 40 from the flat wall 240 of the first projection 24’. The inclined wall 241 therefore acts on the elastic fingers 41 , causing their bending inwards due to the wedge effect, in order to keep them in said closed configuration.

If the spring 42 is compressed along the first direction X1 , the elastic fingers 41 advance into the troncoconical shaped cavity and can pass into said semi-open or open configuration, following the profile of the inclined wall 241 of the first projection 24’.

Furthermore, in the embodiment shown in Figures 1 - 6, the three elastic fingers 41 are arranged along the circumference of the hole of the ring 40 at 120° from each other, so as to ensure a distributed grip on the outer cylindrical surface of the syringe 100. In fact, the syringes commonly on the market are usually made of plastic materials. Therefore, an incorrect distribution of the loads could cause an excessive ovalisation, with consequent obstruction of the passage of the piston 102. Flowever, in alternative embodiments the number of elastic fingers 41 can be different from three and they can have shapes different from the one described.

With reference to Figures 11 - 12, it can be seen that the insertion of a syringe 100 into the syringe holder 1 takes place after removing the locking mechanism 5. The syringe 100 is therefore inserted from the rear part of the housing 20, to then be locked in the pincer element 4.

Such locking takes place by pressing the ring 40 of the pincer element 4, and therefore compressing the spring 42, so that the pincer element 4 passes into said open configuration. Once the body 101 of the syringe comes in abutment against the front portion of the casing 2, the pressure force on the ring of the pincer element 4 is removed, and the elastic fingers 41 spontaneously return due to the elastic return thrust of the spring 42 towards the closed configuration, and press on a portion of the body 101 , keeping it in place.

Subsequently, the locking mechanism 5 is inserted in place.

In the example shown in the figures, the stem 103 of the syringe 100 has fins 1031 , which, during the insertion step, are aligned along the shorter side of the elliptical section, so as not to interfere with the operation of the syringe holder 1. In fact, the clips 51 operate along the shorter side because on the longer side there are the tracks 220, 230 on which the respective racks 3, 8 slide. Therefore, also the possible fins of the stem 103 of the syringe 100 must be oriented/rotated in that direction.

Subsequently, the needle of the syringe 104 is coupled to the body 101 , being inserted inside the hole 21 , and the syringe holder 1 coupled to the syringe 100 can be used to inject fluid into a tissue.

Referring to Figures 15 - 17, the schematic operation of the syringe holder 1 - syringe 100 assembly for injecting the fluid contained in the body 101 takes place as follows.

The assembly can be gripped by the operator, taking the syringe holder 1 with the thumb arranged on the casing 2, the index finger arranged in correspondence of the first lever 7 and the middle finger arranged in correspondence of the trigger 10. In particular, the grip can involve the following four points of support of the operator’s hand: a first gripping point between the distal interphalangeal region, in its medial part, and the palmar region of the distal phalanx of the middle finger a second gripping point between the distal interphalangeal region and the distal palmar region of the index; a third gripping point in correspondence of the palmar region of the distal phalanx of the thumb; and a fourth gripping point in correspondence of the interosseous dorsal region between the first and second metacarpus of the hand.

The grip is particularly ergonomic, as it follows the natural position of the fingers. Furthermore, thanks to the close position of the fingers, it is possible to ensure that the needle 104 is kept in the tissue in a stable position for the entire time of the injection.

Thanks to the presence of the second rack 8 and the related second locking and releasing means 9, it is possible to carry out an initial suction step, shown in Figures 15 and 16.

Such step is particularly important in the case of injections of fluids for aesthetic medicine applications, as it allows to verify that the needle 104 of the syringe 100 has not pierced a blood vessel. In fact, if the perforation of a blood vessel occurs, the suction by the syringe 100 would cause the suction of small quantities of blood, visible to the operator, for example at the openings 25.

In a first configuration (shown in Figure 23), prior to suction, the carriage 11 is arranged in abutment against the casing 2, the third spring 910 and the fourth spring 911 are in a rest position, and the second pawl 90 is distant from the second rack 8.

By acting only with the middle finger on the carriage 11 it is possible to make these elements pass into a second configuration (as shown in Figure 16).

In particular, it is possible to start a translation of the carriage 11 along the second direction X2, to bring the second pawl 90 closer to the second rack 8. This involves an extension of the horizontal spring 911.

With the same movement, an anticlockwise rotation to the trigger 10, and a related compression of the third spring 910 are also imparted. This induces the occurrence of a related rotation between the connecting rod 92 and the trigger 10, which involves an anticlockwise rotation of the second pawl 90, until the second pawl 90 engages a tooth 80 of the second rack 8. So that, by continuing to press on the carriage 11 , the same middle finger causes the backwards translation of the second rack 8, thanks to the action of the second pawl 90, and, consequently, the translation of the stem 103 of the syringe along the second direction X2, inducing the suction of any fluid from the patient’s tissue. Advantageously, since the teeth are spaced by a distance equal to about 3 mm, it is possible to control such suction in a fine manner, allowing the stem 103 to perform a stroke equal to precisely 3 mm, i.e. equal to the distance between one tooth 80 and the previous one. In particular, the maximum stroke of the translating trigger is determined not by the distance between teeth 80 of the second rack 8, but by the mechanical stops present on the casing 2. In addition, it must be taken into account that the suction, although having approximately the same stroke of 4/5 mm, it must be able to be repeated for different positions of the stem, hence the need to have a toothing for the random gear meshes.

Once the suction is complete, the middle finger can move away from the trigger 10 and from the carriage 11, and by elastic return of the springs 910 and 911 , the elements 90, 11 , 10 of the syringe holder 1 return to the first configuration (shown in Figure 15). In other words, by removing the middle finger from the trigger and repositioning it keeping the grip on the syringe holder 2, like a pen, both triggers 10, 11 return to their respective initial positions due to the effect of two springs.

The suction step can be repeated several times, even after injection steps, until the body 101 of the syringe 100 is completely emptied (shown in Figure 17).

The injection step is shown in Figures 18 and 19, and is guided by the action of the first lever 7 and the related first locking and releasing means 6 on the first rack 3.

In particular, in a first configuration, or rest configuration, the first spring 610 and the second spring 611 are in a rest position (shown in Figure 18), and the first pawl 60 is spaced from the first rack 3.

By pressing with the only index finger on the first lever 7, it is obtained an anticlockwise rotation of the first lever 7 and the passage of the system into a second configuration, or injection configuration (shown in Figure 19).

In fact, the first spring 610 is compressed, with consequent approach of the first lever 7 to the outer wall of the casing 2, and consequently of the first pawl 60, to the first rack 3 until the first pawl 60 engages on a tooth 30 of the first rack 3.

By continuing to press on the first lever 7, with the first pawl 60 engaged on the tooth 30, the second spring 611 is brought into compression. This involves dragging the first rack 3 by the first pawl 60 along said first direction X1 and the consequent translation of the stem 103 of the syringe 100 in said first direction X1 , with related passage of the fluid from the body 101 of the syringe 100 into the patient’s tissue.

Therefore, by pressing with the index finger on the lever 7 in anticlockwise direction downwards, it is determined the rotation of the lever 7 itself, which acts as a rocker arm, and, through the first pawl 60 (which acts as a connecting rod), generates the advancement of the first rack 3 (which acts as a piston), hence the injection. Therefore, there is the advantage of injecting the fluid with the index finger without leaving the firm and secure grip of the syringe holder.

In particular, the advancement of the first injection rack 3 is intermittent of the “ratchet” type. In other words, such advancement continues as long as the index finger can press on the lever 7 imposing a clockwise motion. The rotation of the lever 7 can reach, at most, up to the upper dead spot of the crank gear, whose stroke coincides or is an integer multiple of the length of about 3 mm of the single tooth.

At this step, a stop follows, hence the control lever is recharged to carry out a new advancement step. Therefore, the fluid injected by the syringe depends on the hourly law imposed by the index finger.

In particular, the drive force of the mechanism is amplified by the multiplying effect of the first lever 7, and the first rack 3 kinematically assumes the role of the piston of a thrust crank gear, and is moved along said first direction X1.

Advantageously, thanks to such configuration, it is obtained a fine adjustment of the injection force and flow rate of the injected fluid, both of which can be controlled directly by the operator.

In fact, each complete angular stroke of the first lever 7 corresponds to a defined stroke of the stem 103 of the syringe 100, and consequently to a determined volume of fluid injected for each given diameter of the body 101 of the syringe 100. In one embodiment, the maximum angular stroke of the first control lever 7 can be equal to about 5°. Under these operating conditions, the volumetric flow rate, i.e. the amount of fluid injected in the unit of time, depends solely on the direct control of the movement of the index finger, which is implemented by the operator.

Therefore, by controlling the displacement over time, i.e. the rotation speed of the first lever 7, the resisting force represents a variable disturbance, since it depends on the tissue, as well as on the needle section and the viscosity of the fluid, but the management of all these operational parameters are delegated to the perception and sensitivity of the operator.

The syringe holder 1 thus described can therefore be used with a syringe 100, in particular a syringe 100 whose body 101 contains a fluid to be injected for cosmetic treatments of aesthetic medicine, such as for example a filler product or a fluid containing botulinum toxin. By way of example, such filler product may contain hyaluronic acid.

Therefore, the syringe holder 1 can be used for cosmetic use.

In particular, such cosmetic use may provide the implementation of a cosmetic method including the following steps:

A. inserting the syringe 100 in the housing 20 and coupling the stem 103 with the first coupling device 5;

B. perforating the tissue where injecting the cosmetic treatment fluid;

C. acting on the second locking 8, 10 and releasing 9, 10 means to generate a suction force in the body 101 and implementing a safety suction; and D. acting on the first locking and release means 6, 7 to inject a quantity of cosmetic treatment fluid into said tissue.

In particular, the insertion step can take place by sliding the syringe 100 without a needle 104 inside the housing 20 in the first direction x1 until the tip of the syringe 100 abuts against the front end 201 of the casing 2. During such insertion step, the body 101 can be coupled to the pincer element 4. Once the insertion of the syringe 100 into the syringe holder 1 has been completed, the needle 104 can be inserted through the central hole 21.

Tissue perforation is a superficial perforation, as fillers or botulinum toxin must be injected at the level of the dermis.

The syringe holder just described allows to manage with sensitivity the flow of the fluid through the syringe cylinder and the needle, regardless of the viscosity of the fluid, the gauge and the length of the needle or cannula, leaving discretionary autonomy to the operator, not only on the force to be impressed on the stem, but also to determine the amount of liquid injected into the site in relation to the consistency of the imbibition in the biological tissue during the operation.

This allows to use needles of reduced gauge even for fluids with high viscosity or high elastic modulus, which otherwise could not be used in traditional syringes due to the excessive force to be applied by the thumb (palm) of the operator acting on the stem.

Such syringe holder also allows the use of common filler and/or botulinum toxin syringes available on the market, without any modification or removal of the stem.

The syringe holder according to the invention also has an ergonomic handle, thanks to the presence of four support points, which allow its handling with one hand, in the same way as a common writing pen, or brush, or scalpel, drastically reducing the distance of the fingers from the injection site.

In particular, thanks to the pen grip, such syringe holder allows to perform injections with precision and control of the injection site and the path of the needle and/or cannula without any change of posture. Furthermore, advantageously, the syringe holder just described allows to carry out the safety suction operation thanks to the presence of the negative pressure lever that can be controlled with the middle finger.

Finally, thanks to the use of the syringe holder 1 , the cosmetic treatment method is at zero risk.

In the foregoing, the preferred embodiments have been described and variants of the present invention have been suggested, but it is to be understood that those skilled in the art will be able to make modifications and changes without thereby departing from the relative scope of protection, as defined by the attached claims.