FIELD OF THE INVENTION

[01] The present invention generally relates to systems and methods for treating eye and brain disorders, specifically, the present invention relates to visual and audible regimes designed to stimulate brain related pathways.

BACKGROUND OF THE INVENTION

[02] The invention may apply to several medical conditions, general relevant background is provided for some of them.

[03] Amblyopia: Amblyopia is characterized by poor or indistinct vision in an eye. It is one of the most common disorders of the visual system in childhood, affects 1-5% of the population, and is generally associated with a history of strabismus, anisometropia, or form- deprivation in early life [1]. Amblyopia is a developmental problem in the brain, not an organic problem in the eye. The part of the brain corresponding to the visual system from the affected eye is not stimulated properly, and develops abnormally.

[04] Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is a widely used brain mapping technique, which can be used to evaluate the neural activity in the brain by measuring the blood flow to the local vasculature. More recently, fMRI has enabled the noninvasive investigation of brain cortical function in human amblyopia. It has been found that amblyopia is associated with lesions in the striate cortex (Brodmann areas 17) and lateral geniculate nucleus (LGN) [Li C, Cheng L, Yu Q, Xie B, Wang J. Relationship of Visual Cortex Function and Visual Acuity in Anisometropic Amblyopic Children. Int J Med Sci 2012; 9(1): 115-120].

[05] Adult brain plasticity, although possible, remains more restricted in scope than during development. However, there may be conditions under which circuit rewiring may be facilitated in the mature brain. At a cellular and molecular level, adult plasticity is actively limited. Some of these "brakes" are structural, such as perineurologicalnal nets or myelin, which inhibit neurite outgrowth. Others are functional, acting directly upon excitatory- inhibitory balance within local circuits. [Removing Brakes on Adult Brain Plasticity. The Journal of Neurologicalscience, November 10, 2010 · 30(45): 14964 -14971]. It is contemplated that plasticity in childhood and adulthood may be induced either by lifting these brakes through environmental removal of brakes to enable recovery of vision through the increase in brain plasticity after being exposed to customised video content.

[06] It is also argued that the plastic potential of neural networks can be engaged late in life by acutely regulating "functional" E/I transmitter release. Manipulations that locally reduce inhibition in adulthood have been found to restore a heightened visual plasticity (He et al., 2007; Sugiyama et al., 2008; Harauzov et al., 2010) (Fig. 1). One action of endogenous neurologicalmodulator release such as norepinephrine, acetylcholine, serotonin, or dopamine may be to adjust a favorable E/I balance (Bear and Singer, 1986; Kasamatsu, 1991; Kilgard and Merzenich, 1998; Bao et al., 2001; Weinberger, 2007; Maya Vetencourt et al., 2008; Goard and Dan, 2009). In a striking example, chronic treatment with the serotonin reuptake inhibitor (SSRI) fluoxetine restores visual function in amblyopic adult rats apparently by resetting E/I balance (Maya Vetencourt et al., 2008). This neurologicalchemical milieu can act in a cell-specific manner during periods of heightened arousal or focal attention (McCormick, 1989; Gil et al., 1997; Kawaguchi, 1997; Kawaguchi and Shindou, 1998; Xiang et al., 1998; Hsieh et al., 2000; Froemke et al., 2007).

[07] Action video game play may improve the efficiency of probabilistic inference in neural circuits, which in turn would provide a mechanistic explanation for the broad transfer such training engenders (Green et al., 2010b). These plastic changes have been shown to be long-lasting, with beneficial effects noted 6 months to 2 years after the end of intervention (Feng et al., 2007; Li et al., 2009b).

[08] Specific training therapies: the potential importance of active concordant binocular stimulation (stereo displays). In addition to the patching of the fellow eye, treatment of amblyopia has for over a century included various training strategies designed to improve the vision of the amblyopic eye, to reduce suppression of this eye when both eyes are open and/or to train fusion and binocular vision.

[09] Therapies directed towards both the reduction of the severity of amblyopia and the enhancement of binocular vision may be more successful than procedures designed just to reduce amblyopia. Encouragement for the design and use of therapies directed towards binocular function receives strong support from animal work, which demonstrates retention of binocular connections even after two months of monocular deprivation (Freeman & Ohzawa 1988). A recent treatment study as yet published only in abstract form (Mansouri et al. 2008) that employed binocular coherent motion stimuli revealed intact binocular interactions in eight amblyopic subjects when the information content of the stimuli presented to the fellow eye was reduced by an appropriate amount that was titrated individually for each subject. Moreover, a pilot study of binocular training with such specifically matched dichoptic stimuli produced both a significant improvement of the visual acuity of the amblyopic eye and of binocular vision.

[10] Shams, Kamitani, Thompson and Shimojo suggested the brain potentials for the illusory flash (i.e. an auditory stimuli that followed a visual stimuli, were qualitatively very similar, suggesting that the same mechanism underlies both stimuli (audio and visual). These results suggest that the activity in the visual cortex can be modulated by sound. These results taken altogether suggest that the activity along the visual cortex can be modulated by the auditory stimulation. Therefore, the multisensory integration already seems to be at work at the level of modality-specific areas. (Sound alters visual evoked potentials in Humans, Neurologicalreport; Vol. 12 No 17 4 Dec. 2001).

[11] Strabismus: According to the American Association for Pediatric Ophthalmology and Strabismus (AAPOS), Strabismus is defined as any misalignment of the eyes, and is estimated to affect 4% of the U.S. population has strabismus. Strabismus is most commonly described by the direction of the eye misalignment; common types of strabismus are esotropia, exotropia, hypotropia, and hypertropia. Strabismus can also be described by its cause. The 3 cranial nerves (III, IV, VI) responsible for eye movement can be weak or palsied and cause strabismus. Some examples of paralytic strabismus include third nerve palsy and superior oblique palsy. Eye misalignment can cause amblyopia in children. When the eyes are oriented in different directions, the brain receives 2 different visual images. The brain may ignore the image from the misaligned eye to avoid double vision, resulting in poor vision development of that eye. Also, an eye that sees poorly tends to be misaligned.

[12] Vision Therapy includes the eye muscle training methods, it includes training and rehabilitation of the eye-brain connections (neuro-lplasticity) involved in vision. According to AAPOS, vision therapy is defined as an attempt to develop or improve visual skills and abilities; improve visual comfort, ease, and efficiency; and change visual processing or interpretation of visual information. An optometnc vision therapy program consists of supervised in-office and at home reinforcement exercises performed over weeks to months Clinical and research developments in Vision Therapy are allied with developments in neuroscience and research continues (www.trabismus.org; www.aapos.org).

[13] Glaucoma and Optic Nerve Atrophy:Glaucoma is a complicated disease in which damage to the optic nerve leads to progressive, irreversible vision loss. Glaucoma is the second leading cause of blindness. The increased pressure, called intraocular pressure, can damage the optic nerve, which transmits images to the brain. If damage to the optic nerve from high eye pressure continues, glaucoma will cause permanent loss of vision. Without treatment, glaucoma can cause total permanent blindness within a few years.

[14] Glaucoma usually occurs when pressure in your eye increases. This can happen when eye fluid isn't circulating normally in the front part of the eye. Normally, this fluid, called aqueous humor, flows out of the eye through a mesh-like channel. If this channel becomes blocked, fluid builds up, causing glaucoma. Less common causes of glaucoma include a blunt or chemical injury to the eye, severe eye infection, blockage of blood vessels in the eye, inflammatory conditions of the eye, and occasionally eye surgery to correct another condition. Glaucoma usually occurs in both eyes, but it may involve each eye to a different extent.

[15] There are two main types of glaucoma: (a) Open-angle glaucoma. Also called wide- angle glaucoma, this is the most common type of glaucoma. The structures of the eye appear normal, but fluid in the eye does not flow properly through the drain of the eye, called the trabecular meshwork. (b) Angle-closure glaucoma. Also called acute or chronic angle-closure or narrow-angle glaucoma, this type of glaucoma is less common but can cause a sudden buildup of pressure in the eye. Drainage may be poor because the angle between the iris and the cornea (where a drainage channel for the eye is located) is too narrow (sources: www.webmd.com, www. Glaucoma.org)

[16] Parkinson's & Alzheimer diseases 'Mahony, and Rowan suggest that , auditory endogenous Event-Related Potentials (ERPs) and flash visual evoked potentials (VEPs) were recorded in 26 elderly patients with idiopathic Parkinson's disease (PD), 14 with dementia and 12 non-demented, 16 elderly patients with Alzheimer dementia (AD) and 15 cognitively intact controls. ERP P3 and flash- VEP N2, P2 and delta (P2-P1) latency measures were significantly increased in the demented PD group compared with controls. The ERP P3 latency was also significantly delayed in the AD group compared with controls (Gerontology. 1993;39(4):228-40.; Parkinson's dementia and Alzheimer's dementia: an evoked potential comparison).

[17] Olichneya, Yanga, and Kutasd, reviewed several abnormalities in the cognitive ERPs of AD patients. They suggest that the sensitivities of a number of ERP components have great promise in the detection and quantification of neurological dysfunction in the pre- symptomatic stages of Alzheimer's disease. They also refer to that, several investigators have suggested that AD may be primarily a disorder of the synapse and neurological plasticity. ("Cognitive Event-Related Potentials: Biomarkers of Neurological Dysfunction Cognitive Event-Related Potentials"; J Alzheimers Dis. 2011 ; 26(0 3): 215-228. doi: 10.3233/JAD- 2011-0047)

[18] ERP and VEPs were discussed as means to identify and quantify neurological dysfunction in AD patients. It is contemplated that plasticity of neurological connections may be promoted using customized auditory and visual stimulation, in the form of specific video and audio presentations and stimulus, serving as light and sound stimulations, as well as cognitive stimulation due to the engagement of the patient in the presented content .

[19] ADD and ADHD: Attention deficit hyperactivity disorder (ADHD) and attention deficit disorder (ADD) symptoms may begin in childhood and continue into adulthood. ADHD and ADD symptoms, such as hyperactivity, impulsiveness and inattentiveness, can cause problems at home, school, work, or in relationships. Scientists are not sure what causes ADHD, although many studies suggest that genes play a large role. Like many other illnesses, ADHD probably results from a combination of factors. In addition to genetics, researchers are looking at possible environmental factors, and are studying how brain injuries, nutrition, and the social environment might contribute to ADHD. (source: National Institute For Mental Health, www.nimh.nih.gov). Structural and functional imaging research on the neuro-chemistry of ADHD implicate the catecholamine-rich fronto- sub cortical systems in the pathophysiology of ADHD. The effectiveness of stimulant medication, along with animal models of hyperactivity, also point to catecholamine disruption as at least one source of ADHD brain dysfunction. [20] A 10-year study by National Institute of Mental Health found that brains of children and adolescents with ADHD are 3-4% smaller than those of children who don't have the disorder - and that medication treatment is not the cause (JAMA 2002 Oct 9; 288(14): 1740- 8).

[21] Basic neuro-imaging research is being conducted to further delineate the pathophysiology of ADHD, determine diagnostic utility of neuro-imaging, and elucidate the physiological effects of treatment (source: National Resource Center on ADHD; www.help4adhd.org).

[22] A study evaluating visual function and color vision in adults with ADDVADHD disorders, found that the ADHD group of subjects reported significantly more problems in 4 of 8 areas on visual Activities Questionnaire: depth perception, peripheral vision, visual search and visual processing speed. Further analyses of the visual Activities Questionnaire items revealed that the ADHD group endorsed more visual problems associated with driving than controls. Color perception difficulties on the Hue Test were restricted to the blue spectrum in the ADHD group. Hue Test and Quick Test of Cognitive Speed results revealed slower processing of visual stimuli in the ADHD group. This study may support the idea of the potential impact of these visual problems on driving performance. (J Optom. 2014 Jan- Mar;7(l):22-3).

[23] STROKE: Ischemic stroke produces cell death and disability, and a process of repair and partial recovery. Plasticity within cortical connections after stroke leads to partial recovery of function after the initial injury. Physiologically, cortical connections after stroke become hyperexcitable. (Plasticity of cortical projections after stroke. Neuroscientist. 2003 Feb;9(l):64-75. Stroke induces a process of axonal sprouting in neighboring or connected cortical neurons that is associated with repair and recovery. Maintaining tissue perfusion in the area surrounding the infarct could hasten or augment synaptic plasticity and functional recovery after stroke. (Local Hemodynamics Dictate Long-Term Dendritic Plasticity In Peri- Infarct Cortex., J Neurosci. 2010 Oct 20; 30(42)).

[24] Thus, there is a long-felt need for providing a "one size fits all", easy to use, visual and/or audible regimes for promoting brain related pathway perfusion for treating the above mentioned medical conditions. SUMMARY OF THE INVENTION

[25] A system for treating brain related medical conditions of a patient comprising:a head- mountable apparatus comprising at least one lens having a see-through field-of-view;at least one programmable component configured to display at least one artificial visual stimulus seen by said patient in said see-through field-of-view;a database containing at least one predetermined protocol for controlling said artificial visual stimulus;wherein said programmable component contains instructions for affecting the image presentation of said artificial visual stimulus in least one portion of at least one lens according to a predetermined regime.

[26] The medical conditions are selected from the group comprising of, but not limited to, amblyopia, strabismus, glaucoma, Parkinson's disease, ischemic stroke, Alzheimer, other brain diseases and conditions and any combination thereof.

[27] The system enhances blood flow and perfusion to the brain by means of the artificial visual stimulus protocol.

[28] The system is characterized by the following: at least one of lens is opaque; at least one near eye light emitting component of a list comprising: LED, bulb light or fluorescent, wherein said light emitting device is controlled by said programmable component to provide for a visual stimuli; a user interface device allows the user to alter the protocol affecting the stimuli levels; and the system can be controlled remotely.

[29] The programmable component is further configured to provide at least one audible stimulus, to provide said artificial visual stimulus and/or audible stimulus wirelessly. The artificial visual stimulus is dynamically adaptive to the ambient lighting conditions.

[30] The system uses the results of a computerized refractive eye exam to automatically affect the protocol of visual stimuli provided by the system.

[31] The level of at least one parameter of the artificial visual stimulus out of a list comprising; brightness, contrast, saturation, blur or sharpness, is altered dynamically with respect to the characteristics of at least one visible element in the presented image itself. [32] According to the protocol, for a predetermined period of time, no stimuli is provided to allow for the user's organs to rest. Furthermore, for a predetermined period of time, at least one display area is darkened to allow for the user's organs to rest.

[33] The actual viewing area on at least one display is partial, thereby allowing for shifting of the viewing area in a direction out of a list comprising: upwards, downwards, sideways or any combination thereof, with respect to the natural viewing plain.

[34] A system for training the eye muscles, comprising:a controller connectable to a streaming video content; a memory component for storing a regimen; at least one near eye display having a display area; wherein at least one moving object superimposed on the video content in real time, is displayed on at least one near eye display, in accordance to a predetermined regimen.

[35] The system provides an audio stimuli out of a list comprising: spoken description of the objet, a sound commonly associated with the moving object, a distinct sound; in conjunction with the superimposed object.

[36] The regimen alters a presented image's properties to at least one near-eye display our of a list comprising: brightness, contrast, saturation, monochromatic or any combination thereof. Also, the regimen alters a size of the presented image's at least one near-eye display and the regimen alters a position of the presented image's at least one near-eye display.

[37] The system enhances blood flow and perfusion to the brain by means of the artificial visual stimulus protocol.

[38] The system is configured to substantially isolate user's eyes from external visual disturbances.

[39] The system further comprising a data logger.

[40] An apparatus for treating brain related medical conditions of a patient comprising:a head-mountable apparatus comprising at least one lens having a see-through field-of-view;at least one programmable component configured to display at least one artificial visual stimulus seen by said patient in said see-through field-of-view;wherein said system further comprises a database containing at least one predetermined protocol; and further wherein said artificial visual stimulus is derived from said at least one predetermined protocol.

[41] The apparatus can be powered by a battery cell,wirelessly powered, powered from an outlet within a device having an outlet from the group comprising: HDMI, USB, Mini-USB and Micro USB, or any combination thereof.

[42] The apparatus comprises a controller unit and a wireless receiving unit, and can be controlled remotely. It also comprises a data logger.

[43] A head mounting apparatus for positioning a video display component in from of a person's eye, for treating a brain related medical condition, comprising: an ergonomic fixing head brace for a near eye display component; and a compartment for fixing an electronic image display component;wherein said compartment is adapted for replacing the electronic image display component, when the electronic display is intended to be reused by more than one person.

[44] A brain and eye stimulation software application for use with a mobile computerized device, for altering the video image as presented on at least one near-eye video display comprising at least: (a) one digital video filter, for alternating at least one characteristic; (b) triggering changes of the display properties; and(c) an on screen display of a superimposed object; wherein the stimulation is achieved by altering the presentation of an image on said near eye display in accordance to a protocol operated by said software application.

[45] The software application alternates the viewed image properties on at least one display of the lens having a see-through field-of-view, and is obtained by way of altering at least one parameter of the video data sent to least one display of the binocular device.

[46] The software application the shifts at least one image presented on at least one display, such shift may be up-down-left-right, whereas the shift is achieved by means of a command to a controller (or driver) connected to said displays or screens.

[47] The software application comprises two display areas; wherein a dichoptic view is achieved by a video data stream that is SIDE by SIDE encoded, Frame Sequential encoded or Field Sequential encoded. [48] A binocular video eyewear system for treating a medical condition comprising;at least two display components;at least two display driver components;a controller; anda memory component connected to said controller;wherein according to a predetermined regimen, the controller commends a display driver to alter of at least one image parameter of at least one display, out of a list comprising: brightness, contrast, saturation, monochromatic or any combination thereof.

[49] A method for training the brain and visual system using involuntary learning by a passive user comprising: obtaining a set of near-eye video display, having at least one display area having a see-through field-of-view; repetitive presenting of a superimposed image on said at least one display area; and providing a non-visual stimuli in conjunction with said superimposed image; wherein the user associates the image with the sound, thus the user's brain experiences perceptual learning without voluntary engagement of the user.

BRIEF DESCRIPTION OF THE DRAWINGS

[50] In order to understand the invention and to see how it may be implemented in practice, several embodiments will now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which:

[51] FIG. 1 schematically presents the system for the visual stimulation of the brain.

[52] FIG. 2 schematically presents the system for the visual stimulation of the brain,said system comprises a software application (APP) and by way of illustration, a Tablet PC.

[53] FIG. 3 schematically presents thesystem comprising a visual stimuli generator and a visual stimuli superimposed on the general viewing area of a pair of spectacles.

[54] FIG. 4 illustrate an embodiment of a predetermined protocol.

DETAILED DESCRIPTION OF THE PREFERRED EMBOD EVENTS

[55] The following description is provided, alongside all chapters of the present invention, so that to enable any person skilled in the art to make use of said invention and sets forth the best modes contemplated by the inventor of carrying out this invention. Various modifications, however, will remain apparent to those skilled in the art, since the generic principles of the present invention have been defined specifically to provide a system for treating brain related medical conditions of a patient.

[56] The present invention uses a combination of stimuli means and relies on a combination of physiological phenomena and provides a novel treatment approach along with a system and a method. The invention uses novel visual and audible stimuli protocols, which may be materialized by controlling specific characteristics of visual and audio data as presented to the human senses. In other words, the invention uses brain stimulation, based on controlling the levels and characteristics of the light energy and acoustic energy. In some embodiments, the present invention may also utilize mechanical-physical stimulation such as direct or indirect mechanical vibration stimuli.

[57] The present invention facilitates activation of brain areas using audio-visual stimuli, while the user is principally PASSIVE, e.g. is not required to take a voluntary action to affect the treatment. Furthermore, the passive nature of being exposed to an audio-visual content, allows for the user to be focused on the presentation of the content, thereby being FOCUSED on the stimuli. This focus, contributes to the effect of the stimuli in various areas of the brain, including ones involved in interpretation of data.

[58] The present invention facilitates for a novel treatment that stimulates the activity of residual or deficient neurological connections in the visual system and other brain areas, while at the same time it encourages formation of new neurological connections. By way of example, results from a prospective clinical study aimed to evaluate the efficacy of the invention as a possible treatment for Amblyopia, indicated significant improvement of 2 LogMar lines in visual acuity of the subjects within 4 weeks of treatment. The reactivation of the Amblyopic eye visual pathway facilitates overcoming the suppression by the fellow eye in the various sections of the visual system (LGN and VI), and provides proof the stimuli indeed promoted brain plasticity.

[59] The present invention affects the user's blood flow and perfusion level in the brain, which are elevated as a result of the increase in Nitric Oxide produced. This effect reduces user fatigue while using the disclosed invention, contributes to the overall metabolism in the visual system, and thus contributes to re-generation of neurological connections. Watching video content using the present invention exposes the user to light and acoustic energies. It evokes neural activity in the retina at several levels, an activity later translated to signals represented in the LGN and the cortex. The Present invention displays to the Amblyopic eye a visual stimulus (dynamic video image) characterized by (i) increased contrast, combined with; (ii) increase luminance i.e. brightness, thus affecting increased electric signaling. The increased signal, "overcomes" the inherent noise of the Amblyopic eye in parts of the visual system, a noise resulting from the loosening of the neurological connections, in the neurological driven by the Amblyopic eye.

[60] The present invention utilizes stimuli affecting a passive visual learning. Overlay images, superimposed on to the video content presented, and traveling through the frame, stimulate the visual cortex and are believed to contribute to driving plastic changes, as the brain "learns" the travel patters as the eyes follow the objects travel. As the travel path is repetitive, and is associated with a pre-alerting sound effect, it is assumed to affect learning.

[61] The present invention may include auditory stimuli. The use of auditory stimuli, with increased intensity to any of the eyes for example, serves three purposes: (a) The auditory stimulus secures the patient's attention to the visual stimuli, which is enhanced by the auditory input (music, sound effects, meaningful talking of characters viewed on the displays). The patient is therefore drawn into the visual experience, and thus is highly attentive to the visual stimuli. (b) The auditory stimulus compensates for the poor visual capacity, especially at early stages of the treatments period (until enough improvement in acuity is achieved). It is important to note that the auditory input is instrumental in maintaining the coherence of the watching experience, especially in patients with poor visual acuity at an eye. (c) The auditory stimuli evokes a corresponding neurological response in the visual cortex. Further, stimuli regimens, that includes rest and rebalance intervals. Temporary darkening of both displays of the present invention and indented darkening of any of the displays are intended to improve the effect evoked by the stimuli provided immediately after the period of darkening.

[62] The present invention provides for a novel concept of a PASSIVE treatment, whereas in the preferred embodiments of the invention, the user is merely required to watch and listen to an audio-visual content, and said watching and listening provides for the stimuli to be received, processed and affect the physiology of the user, whiteout requirement for any conscious response or involvement. Therefore, the benefit of the present invention may apply also when used as the user is asleep.

[63] The present invention is claimed to be useful for the treatment of various medical conditions, including amblyopia, strabismus andglaucoma. Strabismus is almost always caused by a limitation of ocular rotations that is due to a restriction of extraocular eye movement (ocular restriction) or due to extraocular muscle paresis. The present invention can be used to "train" the extraocular muscles using tracking of moving objects superimposed on any video content, thus may be an adjunct or even an alternative to surgery, we offer a very compelling, safe, cost effective solution. Treating Glaucoma and Optic Nerve Atrophy - the present invention may be either adjunct and in some cases alternate to available treatments to contribute to eye fluids draining, contribute to reversing optic nerve atrophy, to avoid vision loss.

[64] The present invention is claimed to use the visual and auditory pathways to affect the non-properly functioning neurological connections and or restore and\or stimulate formation of new neurological connections affected by this condition in conjunction or as a surrogate to medication when treating Parkinson's disease.

[65] The present invention is claimed to use the visual and auditory pathways to affect the non-properly functioning neurological connections and or restore and\or stimulate formation of new neurological connections affected by this condition in conjunction or as a surrogate to medication when treating an ischemic stroke.

[66] The present invention is claimed to provide for a novel system and method for affecting the eye muscles to be retract and relax, utilizing regimens comprising; moving objects viewed on at least one screen or display area of a binocular display mean, wherein an eye designated for training follows the viewed moving objects superimposed on any displayed video content in contemporary on what is being watched through the screen or display.

[67] Furthermore, it is the purpose of the disclosed invention, to provide for treatment protocols comprising a regimen of alternating at least one image property, in at least one display or screen connected to source device: hue, brightness, saturations, contracts, color\black and white, resolution, zoom-in, zoom-out, shift left-right-up-down. [68] Furthermore, it is the purpose of the disclosed invention, to provide for alternating a viewed image properties while using a binocular display device, by way of altering at least one parameter, reflecting on the image viewed on at least one display or screen (while leaving the video data arriving from the source device intact). Such alternation of the display properties may be triggered by either command signal delivered to the display from a controller (for example an computer or a Smartphone) or mechanical device (for example a switch). Such alternation of the display properties may be pre-programmed to reflect a predetermined protocol. Such protocol may be embedded in an IC controlling the display or screen operation, or an IC external to said display or screen device.

[69] Furthermore, it is the purpose of the present invention, to provide for visual stimuli in the form of a flicker or a flash, presented on at least one display or screen of a binocular device, in a predetermined or arbitrary sequence, or any combination thereof. Said visual stimuli may be, but not necessarily, stopped, delayed or renewed by a command provided by a triggering device controlled by the viewer, such as a human interface device.

[70] A system as described, comprising a user operated input device, allowing the user to seize, alter and\or restart a visual stimuli presented to him.

[71] Furthermore, it is the purpose of the disclosed invention to provide for a software application to be used with a binocular video eyewear, wherein at least one image viewed on said displays or screens may be shifted up-down-left-right by means of a command to a driver component connected to said displays or screens. The system as described above, whereas the visual stimuli presentation is displayed only on part of the area visible to the user, allowing for altering the position of an image within viewing area either: (a) in a predetermined manager, (b) in an arbitrary manner, (c) in relevance with the otherwise environment's visual inputs.

[72] Furthermore, it is the purpose of the disclosed invention to provide for a dichoptic view binocular video eyewear set for use with video games and for watching video content, either stored in the eyewear or on an external device, or streaming form an external device or streaming directly to the eyewear set by a communication device.

[73] Furthermore, it is the purpose of the disclosed invention to provide for a treatment protocol for use with a dichoptic view binocular video eyewear, said protocol comprising displaying monochromatic image to at least one eye while displaying a color image to fellow eye.

[74] Furthermore, it is the purpose of the disclosed invention to provide for a dichoptic view binocular video eyewear system, said eyewear comprising a, or connected to, an IC and a protocol for displaying visible objects (superimposed or standalone) on at least one display or screen of said binocular video eyewear system, wherein the objects re superimposed on the then displayed image, or on its own (no specific background or superimposing). In addition, upon, before, or after the appearance of such objects, a distinct sound is played to at least one ear, such a sound may be, but not necessarily, a voice calling out the name or description of said object, a sound otherwise associated with it (for example, an image of a dog, accompanied by a dog barking, or the sound of the word DOG).

[75] Furthermore, it is the purpose of the disclosed invention to provide for a software application, administrating the presentation of visual and audible data to a viewerMistener, by way of alternating parameters of the video and\or audio data, as presented on the displays and speakers and or earpieces of said video eyewear system.

[76] Furthermore, it is the purpose of the disclosed invention to provide for a software application as disclosed, wherein personal information of a person are processed so to determine the parameters of a braining or otherwise eye stimulation protocol, any or all of its parameters, including but not limited to: frequency, duration, intensity, pattern, shape or sound or flicker\flashes or appearance of objects or icons on the display and\or associated sounds, and any of the parameters of the image, as displayed.

[77] Furthermore, it is the purpose of the disclosed invention to provide for a protocol for stimuli of the brain and\or eye, comprising at least one appearance of a superimposed visible object, and at least one of the following characteristics: an appearance point, a disappearance point, a movement pattern, movement speed, movement direction. Said protocol preferably but not necessarily be accompanied with a stimuli of an ear, an audible sound, said sound having a duration, intensity, level and tune. It is the purpose of the disclosed invention to provide for a dichoptic stimuli protocol combining any of said stimuli of an eye with any said stimuli of an ear, wherein each eye and each ear may be subject to a different visual or auditable stimuli then the fellow eye or ear. In the system as described above, the visual stimuli is a super-imposed overlay image, presented to at lease of the users eye, and wherein the super-imposed image parameters may be dichoptically presented to each eye, by way of differential movement pattern, size, location or appearance.

[78] Sample protocol

[79] The protocol disclosed may be incorporating several modules. By way of example, a 30 min protocol may comprise 3 sets of 10 modules each (A,B,C). Each module may comprise, by way of illustration, 4 sub modules (A1,A2,A3,A4 and B1,B2 etc .). Each sub- module, may be characterized by specific display parameters, and audio parameters, that may vary between a one eye and the fellow eye, and respective ears. By way of example, in one eye's module Al (duration 30 seconds) the brightness and contrast are 25% above normal, and a superimposed image of a car appears 8 times on the one display, while the sound level to respective ear is elevated by 30%. At the exact same timings, the other display brightness and contrast are decreased by 25%, and the sound level in respective ear is decreased by 30%. In weak eye module A2 (duration 30 seconds) the brightness and color saturation are 15% above normal, and a flickers (white, blue, red, green, yellow, purple, turquoise or any combination thereof) appears 5 times on one display, accompanied by a lightning sound heard only in respective ear. At the exact same timings, the second display brightness and color saturation are decreased by 20%. In one embodiment of the present invention, the protocol comprises alteration of properties only of the image presented to one eye. In another embodiment, a predetermined ratio is maintained between the properties of the image as presented on each display.

[80] The disclosed invention provides for a dichoptic view binocular video presenting eyewear; wherein a dichoptic view is achieved by a video stream of (a) SIDE by SIDE video data or; (b) Field Sequential video data, (c) Frame Sequential video data, (d) video data superimposed on an otherwise transparent lenses, i.e. augmented reality goggles or (e) altering the presentation of the video data by way of altering the properties of a presentation device (display, projector etc.) affecting the properties of an image as presented. Each of the aforesaid may be utilized to affect the dichoptic presentation thus the stimulation of the brain, eyes, ears and any combination thereof.

[81] The disclosed system , comprising at least one near-eye display, wherein the display device is configured to substantially isolate user's eyes from external visual disturbances. [82] A system as described, wherein the display device is mounted on a an everyday like spectacles or is a set of augmented reality spectacles, wherein a visible stimuli is provided to the eye by way of presenting an image, an abstract form or text based stimuli as an add-on to the otherwise visible viewing area. The display device could be any of the following: Google Glass, the Atheer One, GlassUp, Epson Moverio BT-200, Vuzix Ml 00 or otherwise augmented reality devices using micro-projector or pi co-projector components.

[83] A system as described above, wherein the display device is operatively coupled with an audio device configured to provide audio stimulation according to the predetermined regime.

[84] The disclosed system, wherein the controller unit additionally comprises a data storage device adapted to be operatively connected to the controller unit configured to store the predetermined regime.

[85] The disclosed system, wherein the controller unit comprises a graphic processing unit configured to alter at least one image parameter according to the predetermined regime.

[86] The disclosed system , wherein at least one display parameter is selected from the group containing brightness, contrast, saturation, sharpness, resolution, or other conventional parameters and combinations thereof.

[87] The disclosed system, wherein the controller unit is additionally configured to insert at least one overlay of at least one object on at least one displaying area.

[88] The disclosed system, wherein the controller unit is additionally configured to trigger audio data configured to be coherently connected to inserting of at least one generated overlay of at least one object according to the predetermined regime.

[89] The disclosed system , wherein the controller unit is additionally configured to introduce at least one flicker event on at least one displaying area, the flicker may be in the form of a video frames sequence, or an external light source such as an Light Emitting Diode (LED).

[90] The disclosed system , connectable to a visual content source selected from the group consisting of a video game console, cable modem, a television, a computer, a digital camera, a camcorder, a DVD, a mobile phone, a portable media player, an offline video content storage device, and a network online streaming video content.

[91] A system as described above, powered from a DVI, HDMI, USB, Mini -USB or Micro USB outlets of a visual content source selected from the group consisting of a video game console, cable modem, a television, a computer, a digital camera, a camcorder, a DVD, a mobile phone, a portable media player, an offline video content storage device, and a network online streaming video content.

[92] The system as described, wherein the display device is configured to substantially isolate user's eyes from external visual disturbances.

[93] Reference is now made to FIG. l schematically presenting the system for the visual stimulation of the brain. The head set receives a script data comprising a protocol/regime which transmits to the see-through field-of-view displays and to the earpieces. The head set in this example is powered from an USB outlet.

[94] The disclosed system, receiving electrical power from disposable or a rechargeable battery.

[95] The disclosed system, receiving electrical power from a solar energy device.

[96] The disclosed system, wirelessly receiving electrical power from an external source.

[97] The disclosed system, receiving electrical power from a USB outlet of another device.

[98] Reference is now made to FIG.2 schematically presents the system for the visual stimulation of the brain,said system comprises a software application (APP) and by way of illustration, a Tablet PC. The head set receives a script data comprising a protocol/regime from the Tablet PC, which transmits to the see-through field-of-view displays and to the earpieces. The Tablet PC comprises all the necessary software information to run the protocols.

[99] The disclosed system, connectable to a either a PC, Tablet PC, mobile phone, PDA or a screen-less computerized device; wherein said computerized device communicates (by wire or wirelessly) with said system as described above, to provide for a user interface, data storage, video content selection, video data conveying, logging and storing logs of the use of the system, transmitting the logs of the use of the system, or any combination thereof.

[100] The disclosed system, whereas the graphic presentation of the user's interface for operating the system and\or said computerized device connected to the system, is displayed on at least one the display element comprised in the system.

[101] Reference is now made to FIG.3 schematically presents the system comprising a visual stimuli generator and a visual stimuli superimposed on the general viewing area of a pair of spectacles.

[102] The following paragraph disclose preferable embodiments of the present invention:

[103] A system as described above, wherein the image presentation throughout a treatment of an eye or brain related medical condition, is provided by alteration of the display properties such as brightness, contrast, etc., rather than alteration of the content provided.

[104] The system described above, whereas the dichoptic presentation is executed via: (a) at least one display component, (b) at least one display driver component, and (c) a controller component, commanding the driver component to alter at least one display parameter in realtime, by way of example change the brightness or the contrast of the image presented on said display. The controller may command more than one driver, and whereas a driver is connected to a specific display component, said display component will alter the presentation of the image presented by it. A sequence of such commands, preferably but not necessarily different to each driver and thus display, may provide for a dichoptic presentation of the same image, while presented on two display components, by way of example in a set of video goggles. The regimen upon which the controller commends the drivers, may affect a presented image display parameter from the group containing brightness, contrast, saturation, sharpness, resolution, or other conventional parameters and combinations thereof as well as superimposed visual data.

[105] A visual stimuli protocol is provided using the above system, wherein the intensity and regimen of the stimuli, is dynamically adopted to the properties of the then displayed image (e.g., content). [106] A visual stimuli protocol is provided using the above system, wherein the protocol comprises segments whereas at least one the display is a darkened for a predetermined period of time.

[107] A system as described above, comprising at least one light emitting diode (LED) positioned in proximity to the display area, for providing a visual stimuli to the eye. The led may provide for flicker or flash stimuli independently or in conjunction to the audio-visual stimuli via the content.

[108] Reference is now made to FIG.4 illustrate an embodiment of a predetermined protocol. Graph coordinates the dynamic changes in the parameters of the displayed image. The dotted line refers to the contrast. Continuous line refers to the level of brightness. The exposure to the weak eye is mostly done with high contrast and brightness relative to the baseline ("neutral" presentation). The exposure to the strong eye is mostly done with low level of brightness and contrast lower relative to the baseline. The higher peaks, in the continuous line, reflect a state of about over a predeterminedlevel of brightness, meaning bright/white screen. The lower peaks, in the continuous line, reflect a state of about below a predetermined level brightness, meaning dark/black screen. When change is rapid and short, what we get is a flicker effect.

[109] By way of example, we disclose a method for treating an eye or brain related condition, comprising alteration of a visual and audio stimuli provided to a subject, by way of altering the presentation of a visible and audible content presented to a subject, in which at least one of the following occurs at least one time over a treatment session: the Brightness of the presented image to one eye is elevated comparing to a native image; the Contrast of the presented image to one eye is elevated comparing to a native image; the Sharpness of the presented image to one eye is elevated comparing to a native image; the Chroma of the presented image to one eye is elevated comparing to a native image; the Volume level of a sound associated with said presented image, is elevated comparing to a native volume level; the Brightness of the presented image to one eye is decreased comparing to a native image; the Contrast of the presented image to one eye is decreased comparing to a native image; the Sharpness of the presented image to one eye is decreased comparing to a native image; the Chroma of the presented image to one eye is decreased comparing to a native image; the Volume level of a sound connected with said presented image, is decreased comparing to a native volume level; or any combination thereof.

[110] A system as described above, comprising a computerized refractive eye exam (online, embedded or any combination thereof).

[I l l] A system as described above, comprising a computerized refractive eye exam wherein the results of the exam affect the regimen of brain visual stimuli used to treat a brain related medical condition.

[112] A system as described above, wherein the level of at least one parameter of the image's presentation (brightness, contrast, saturation, blur, sharpness) is altered in real time in conjunction to a specific element in the content of the image.

[113] A system as described above, wherein the level of at least one parameter of the image's presentation (brightness, contrast, saturation, blur, sharpness) is altered in real time in conjunction to the image's content lighting level (for example a bright outdoor image, or a dark night image).

[114] A system as described above, wherein at least one stimuli or an image presentation parameter is dynamically with reference to the ambient lighting conditions (dark, well lit or a noisy room) or; an outdoor environment's lighting (noon, evening, night) condition the user is present at a given moment while using the system.

[115] A system as described above, wherein a head mounting apparatus for positioning a video display component in from of a person's eye, is used as a disposable gear and comprises: a body mountable ergonomic fixing and a compartment for fixing an electronic image display. The compartment is designed to allow for easily replacing the electronic image display, for disposing the fixing head brace, when the electronic display is to be used by more than one person. The disposable fixing allows for different users to use the same image display without compromising sanitary of the display. This is useful also to reduce costs, as the display is typically much more expensive then the head mounting brace.

[116] While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof have been shown by way of example in the drawings and the above detailed description. It should be understood, however, that it is not intended to limit the invention to the particular forms disclosed, but on the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention as defined by the appended claims.