Title:
SYSTEMS, APPARATUSES, AND METHODS FOR PREPARATION OF TISSUE SAMPLES
Document Type and Number:
WIPO Patent Application WO/2020/011735
Kind Code:
A3
Abstract:
The invention relates to a method for preparing a tissue sample (101, 201) for microscopy, comprising the steps of submitting a tissue sample (101, 201) to a chemical fixation treatment, mounting the fixed tissue sample (101, 201) inside of an electrically insulating sample holder (102, 202, 902), said sample holder (102, 202, 902) defining a sample volume (121, 221) configured to receive, particularly to hold, the tissue sample (101, 201) within the sample holder (102, 202, 902), the sample holder (102, 202, 902) further having a first opening (117A, 217A) and a second opening (117B, 217B), mounting said sample holder (102, 202, 902) between a first electrolyte chamber (103A) comprising a first electrode (104 A, 904A) and a second electrolyte chamber (103C) comprising a second electrode (104B, 904B), in a clearing step, applying an electric potential difference (voltage) to said first electrode (104A, 904A) and said second electrode (104B, 904B). The invention further relates to a device for electrophoretic clearing, washing and/or staining of a tissue sample (101, 201).
Inventors:
KIRSCHENBAUM DANIEL (CH)
AGUZZI ADRIANO (CH)
AGUZZI ADRIANO (CH)
Application Number:
PCT/EP2019/068307
Publication Date:
February 20, 2020
Filing Date:
July 08, 2019
Export Citation:
Assignee:
UNIV ZUERICH (CH)
International Classes:
G01N1/30; G01N1/36; G01N33/483; G01N33/574; G06K9/00; G06T7/00
Domestic Patent References:
| WO2017096248A1 | 2017-06-08 |
Foreign References:
| US20170176304A1 | 2017-06-22 | |||
| EP3252452A1 | 2017-12-06 | |||
| US20150027894A1 | 2015-01-29 |
Attorney, Agent or Firm:
SCHULZ JUNGHANS PATENTANWÄLTE PARTGMBB (DE)
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