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Title:
SYSTEMS AND METHODS FOR ASSESSING DISEASE BURDEN AND PROGRESSION
Document Type and Number:
WIPO Patent Application WO/2023/239829
Kind Code:
A3
Abstract:
Presented herein are systems and methods that provide semi-automated and/or automated analysis of medical image data to determine and/or convey values of metrics that provide a picture of a patient's risk and/or disease. Technologies described herein include systems and methods for analyzing medical image data to evaluate quantitative metrics that provide snapshots of patient disease burden at particular times and/or for analyzing images taken over time to produce a longitudinal dataset that provides a picture of how a patient's risk and/or disease evolves over time during surveillance and/or in response to treatment. Metrics computed via image analysis tools described herein may themselves be used as quantitative measures of disease burden and/or may be linked to clinical endpoints that seek to measure and/or stratify patient outcomes. Accordingly, image analysis technologies of the present disclosure may be used to inform clinical decision making, evaluate of treatment efficacy, and predict patient response(s).

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Inventors:
BRYNOLFSSON JOHAN MARTIN (SE)
SAHLSTEDT HANNICKA MARIA ELEONORA (SE)
RICHTER JENS FILIP ANDREAS (SE)
SJÖSTRAND KARL VILHELM (US)
ANAND ASEEM UNDVALL (SE)
Application Number:
PCT/US2023/024778
Publication Date:
April 04, 2024
Filing Date:
June 08, 2023
Export Citation:
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Assignee:
PROGENICS PHARM INC (US)
EXINI DIAGNOSTICS AB (SE)
International Classes:
G06T7/11; G06T7/30
Domestic Patent References:
WO2022008374A12022-01-13
Foreign References:
US20220005586A12022-01-06
JP2014006130A2014-01-16
US20200245960A12020-08-06
US7876938B22011-01-25
Other References:
HAIYING GUAN ET AL: "Automatic Hot Spot Detection and Segmentation in Whole Body FDG-PET Images", IMAGE PROCESSING, 2006 IEEE INTERNATIONAL CONFERENCE ON, IEEE, PI, 1 October 2006 (2006-10-01), pages 85 - 88, XP031048579, ISBN: 978-1-4244-0480-3
Attorney, Agent or Firm:
ADATO, Ronen et al. (US)
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