Title:
SYSTEMS AND METHODS FOR CELL MANUFACTURING
Document Type and Number:
WIPO Patent Application WO/2024/039688
Kind Code:
A3
Abstract:
Systems and methods are disclosed for processes related to cell culture and generation. A system for culturing cells a cell culture container comprises a first surface, the first surface being configured for a plurality of cell colonies to continuously adhere thereto throughout a cell culture process; an image sensor configured to capture one or more time-series images of the plurality of cell colonies during the cell culture process; a cell removal tool configured to remove one or more cells from the first surface of the cell culture container during the cell culture process; and a computing subsystem configured to: track one or more characteristics of the plurality of cell colonies based on the one or more time-series images, and control the cell removal tool to remove cells based on the one or more characteristics.
Inventors:
WAGNER MATTHIAS (US)
PILSMAKER CATHERINE (US)
LEE SANGKYUN (US)
LURO SCOTT (US)
SULLIVAN MATTHEW (US)
BERLIN-UDI MAYA (US)
AKSEL DENIZ (US)
NATALE JASON (US)
AIVIO SUVI (US)
AMENDUNI MARIANGELA (US)
PEREIRA ARNALDO (US)
MORGAN STEFANIE (US)
PILSMAKER CATHERINE (US)
LEE SANGKYUN (US)
LURO SCOTT (US)
SULLIVAN MATTHEW (US)
BERLIN-UDI MAYA (US)
AKSEL DENIZ (US)
NATALE JASON (US)
AIVIO SUVI (US)
AMENDUNI MARIANGELA (US)
PEREIRA ARNALDO (US)
MORGAN STEFANIE (US)
Application Number:
PCT/US2023/030293
Publication Date:
April 04, 2024
Filing Date:
August 15, 2023
Export Citation:
Assignee:
CELLINO BIOTECH INC (US)
International Classes:
G01N15/02; G01N15/14; G06N3/088
Domestic Patent References:
| WO2020033871A1 | 2020-02-13 | |||
| WO2021243203A1 | 2021-12-02 |
Foreign References:
| US20170183627A1 | 2017-06-29 | |||
| US20140360576A1 | 2014-12-11 | |||
| US20110297950A1 | 2011-12-08 | |||
| JP6543954B2 | 2019-07-17 | |||
| US8802435B2 | 2014-08-12 |
Other References:
LEI YE, CORY SWINGEN, JIANYI ZHANG: "Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences", CURRENT CARDIOLOGY REVIEWS, BENTHAM SCIENCE PUBLISHERS LTD., NETHERLANDS, vol. 9, no. 1, 1 February 2013 (2013-02-01), Netherlands , pages 63 - 72, XP093158789, ISSN: 1573-403X, DOI: 10.2174/157340313805076278
SATOSHI KAWATA: "Plasmonics for Nanoimaging and Nanospectroscopy", APPLIED SPECTROSCOPY., THE SOCIETY FOR APPLIED SPECTROSCOPY. BALTIMORE., US, vol. 67, no. 2, 1 February 2013 (2013-02-01), US , pages 117 - 125, XP055412621, ISSN: 0003-7028, DOI: 10.1366/12-06861
WANG ET AL.: "Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1", PNAS, vol. 108, no. 45, 8 November 2011 (2011-11-08), pages 18283 - 18288, XP055102609, DOI: 10.1073/pnas.1100893108
CASE ET AL.: "In vitro clonal analysis of murine pluripotent stem cells isolated from skeletal muscle and adipose stromal cells", EXP HEMATOL., vol. 36, no. 2, February 2008 (2008-02-01), pages 224 - 234, XP022425438, DOI: 10.1016/j.exphem. 2007.09.00 3
SATOSHI KAWATA: "Plasmonics for Nanoimaging and Nanospectroscopy", APPLIED SPECTROSCOPY., THE SOCIETY FOR APPLIED SPECTROSCOPY. BALTIMORE., US, vol. 67, no. 2, 1 February 2013 (2013-02-01), US , pages 117 - 125, XP055412621, ISSN: 0003-7028, DOI: 10.1366/12-06861
WANG ET AL.: "Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1", PNAS, vol. 108, no. 45, 8 November 2011 (2011-11-08), pages 18283 - 18288, XP055102609, DOI: 10.1073/pnas.1100893108
CASE ET AL.: "In vitro clonal analysis of murine pluripotent stem cells isolated from skeletal muscle and adipose stromal cells", EXP HEMATOL., vol. 36, no. 2, February 2008 (2008-02-01), pages 224 - 234, XP022425438, DOI: 10.1016/j.exphem. 2007.09.00 3
Attorney, Agent or Firm:
HALSTEAD, David, P. et al. (US)
Download PDF:
Previous Patent: SECURE WEB-BASED PLATFORM FOR DE-CENTRALIZED FINANCING
Next Patent: HETEROCYCLE RBM39 MODULATORS
Next Patent: HETEROCYCLE RBM39 MODULATORS