Title:
SYSTEMS AND METHODS FOR MECHANOGENETIC FUNCTIONAL ULTRASOUND IMAGING
Document Type and Number:
WIPO Patent Application WO/2021/030145
Kind Code:
A3
Abstract:
The present disclosure provides a system for functional ultrasound imaging, where the system comprises: a) an apparatus for delivering a nucleic acid encoding a mechanosensitive ion channel to a target neural cell population in a region of a brain; and b) a functional ultrasound imaging device. The present disclosure provides a method for functional ultrasound imaging.
Inventors:
LEE JIN HYUNG (US)
LIPHARDT JAN (US)
EDELMAN BRADLEY JAY (US)
LIN PETER (US)
LIPHARDT JAN (US)
EDELMAN BRADLEY JAY (US)
LIN PETER (US)
Application Number:
PCT/US2020/045209
Publication Date:
April 01, 2021
Filing Date:
August 06, 2020
Export Citation:
Assignee:
UNIV LELAND STANFORD JUNIOR (US)
LEE JIN HYUNG (US)
LIPHARDT JAN (US)
LEE JIN HYUNG (US)
LIPHARDT JAN (US)
International Classes:
A61K49/00; A61K41/00; A61N7/00; C12N5/0793; C12N13/00
Domestic Patent References:
| WO2012131418A1 | 2012-10-04 |
Foreign References:
| US20160220672A1 | 2016-08-04 | |||
| US20100063397A1 | 2010-03-11 | |||
| US20190308035A1 | 2019-10-10 | |||
| US20110054324A1 | 2011-03-03 |
Other References:
OSMANSKI BRUNO-FÉLIX, PEZET SOPHIE, RICOBARAZA ANA, LENKEI ZSOLT, TANTER MICKAEL: "Functional ultrasound imaging of intrinsic connectivity in the living rat brain with high spatiotemporal resolution", NATURE COMMUNICATIONS, vol. 5, no. 5023, 3 October 2014 (2014-10-03), pages 1 - 14, XP055183074
Attorney, Agent or Firm:
BORDEN, Paula A. (US)
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