Title:
T CELL RECRUITING POLYPEPTIDES BASED ON TCR ALPHA/BETA REACTIVITY
Document Type and Number:
WIPO Patent Application WO/2022/129637
Kind Code:
A8
Abstract:
The present technology provides T cell recruiting polypeptides that specifically bind to the constant domain of a human and of a non-human primate TCR. The present technology also provides nucleic acids, vectors, and compositions. The polypeptides can be used in methods for treatment of cancer.
Inventors:
NEYT KATRIJN (BE)
ROOBROUCK ANNELIES (BE)
STAELENS STEPHANIE (BE)
VAN BELLE TOM (BE)
VERHELST JUDITH (BE)
VAN HOORICK DIANE (BE)
ROOBROUCK ANNELIES (BE)
STAELENS STEPHANIE (BE)
VAN BELLE TOM (BE)
VERHELST JUDITH (BE)
VAN HOORICK DIANE (BE)
Application Number:
PCT/EP2021/086843
Publication Date:
August 10, 2023
Filing Date:
December 20, 2021
Export Citation:
Assignee:
ABLYNX NV (BE)
SANOFI SA (FR)
SANOFI SA (FR)
International Classes:
C07K16/28; A61P35/00; A61P37/00; C07K16/30; C07K16/32
Attorney, Agent or Firm:
HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB, ASSOCIATION NO. 151 (DE)
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