Title:
TACHYKININ ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO1995028418
Kind Code:
A3
Abstract:
The small compounds of the instant invention are tachykinin antagonists. The compounds are highly selective and functional NK3 antagonists expected to be useful in the treatment of pain, depression, anxiety, panic, schizophrenia, neuralgia, addiction disorders, inflammatory diseases, gastrointestinal disorders, vascular disorders, and neuropathological disorders.
Inventors:
HORWELL DAVID CHRISTOPHER
HOWSON WILLIAM
PRITCHARD MARTYN CLIVE
RAPHY JENNIFER
HOWSON WILLIAM
PRITCHARD MARTYN CLIVE
RAPHY JENNIFER
Application Number:
PCT/US1995/003812
Publication Date:
November 16, 1995
Filing Date:
March 27, 1995
Export Citation:
Assignee:
WARNER LAMBERT CO (US)
International Classes:
A61P1/00; A61P9/00; A61K38/00; A61P11/00; A61P25/00; A61P25/04; A61P25/24; A61P25/26; A61P29/00; C07C271/10; C07C271/20; C07C317/28; C07K5/02; C07K5/06; C07K5/065; C07K7/06; (IPC1-7): C07K5/06; A61K38/05
Domestic Patent References:
| WO1992019254A1 | 1992-11-12 |
Other References:
P.BODEN ET AL.: "The Rational Developement of Small Molecule Tachykinin NK3 Receptor Selective Antagonists- The Utilisation of a Dipeptide Cemical Library in Drug Design", BIOORG.MED.CHEM.LETT., vol. 4, no. 14, GB, pages 1679 - 84
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