Title:
TAMPER-RESISTANT TRANSDERMAL OPIOID DELIVERY DEVICES
Document Type and Number:
WIPO Patent Application WO2003070191
Kind Code:
A8
Abstract:
This invention relates to a tamper-resistant transdermal-delivery device comprising an opioid, or a pharmaceutically acceptable salt thereof, and an acyl opiod antagonist, or a pharmaceutically acceptable salt thereof. The transdermal-delivery device allows an analgesically effective amount of the opioid, or a pharmaceutically acceptable salt thereof, to be transdermally administered to a patient. The invention further relates to methods for treating or preventing pain in a patient comprising contacting the skin of a patient in need thereof with the transdermal-delivery device of the invention for an amount of time sufficient to treat or prevent pain. The invention further relates to acyl opioid antagonists.
Inventors:
SHEVCHUK IHOR (US)
CASSIDY JAMES P (US)
REIDENBERG BRUCE (US)
SHARP DALE E (US)
KUPPER ROBERT J (US)
CASSIDY JAMES P (US)
REIDENBERG BRUCE (US)
SHARP DALE E (US)
KUPPER ROBERT J (US)
Application Number:
PCT/US2003/004999
Publication Date:
June 10, 2004
Filing Date:
February 19, 2003
Export Citation:
Assignee:
EURO CELTIQUE SA (LU)
SHEVCHUK IHOR (US)
CASSIDY JAMES P (US)
REIDENBERG BRUCE (US)
SHARP DALE E (US)
KUPPER ROBERT J (US)
SHEVCHUK IHOR (US)
CASSIDY JAMES P (US)
REIDENBERG BRUCE (US)
SHARP DALE E (US)
KUPPER ROBERT J (US)
International Classes:
A61K9/70; A61K31/485; A61K45/06; A61P25/04; A61P25/36; C07D489/08
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