Title:
TARGET SUBSTANCE DETECTION METHOD, TARGET SUBSTANCE DETECTION KIT, AND TARGET SUBSTANCE DETECTION APPARATUS
Document Type and Number:
WIPO Patent Application WO/2019/187467
Kind Code:
A1
Abstract:
Provided is a method for detecting a target substance using interaction via a low-reactive molecular species and using two types of microparticles as proximity probes. The target substance detection method contains: (A) a step of bringing a sample of biological origin into contact with an oxygen sensor to which a first molecule, which specifically binds to a target substance, is bonded; (B) a step of bringing the sample of biological origin into contact with a first solid-phase carrier bearing an oxygen-consuming enzyme and a second molecule that specifically binds to the target substance; and (C) a step of acquiring information coming from the oxygen sensor due to steps (A) and (B).
Inventors:
HOSOKAWA HIROYUKI (JP)
ABE TOMOTERU (JP)
ABE TOMOTERU (JP)
Application Number:
PCT/JP2019/000133
Publication Date:
October 03, 2019
Filing Date:
January 08, 2019
Export Citation:
Assignee:
SONY CORP (JP)
International Classes:
G01N33/542; C12M1/34; C12Q1/02; C12Q1/26; G01N21/64; C07K16/00; C12N9/02; C12N11/00; C12N15/115
Foreign References:
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| JP2006522329A | 2006-09-28 | |||
| JPH1067791A | 1998-03-10 | |||
| JP2007232716A | 2007-09-13 | |||
| JP2013183664A | 2013-09-19 | |||
| US4568649A | 1986-02-04 | |||
| US9393306B2 | 2016-07-19 | |||
| US20080293051A1 | 2008-11-27 | |||
| US7306904B2 | 2007-12-11 | |||
| US7615620B2 | 2009-11-10 | |||
| JP2017171921A | 2017-09-28 |
Other References:
HUANG, P.-H. ET AL.: "Ag@Au nanoprism-metal organic framework-based paper for extending the glucose sensing range in human serum and urine", DALTON TRANSACTIONS, vol. 46, no. 21, 2017, pages 6985 - 6993, XP055641152
ROCCHITTA, G. ET AL.: "Enzyme Biosensors for Biomedical Applications Strategies for Safeguarding Analytical Performances in Biological Fluids", SENSORS, vol. 16, no. 780, 2016, pages 1 - 21, XP055641156
See also references of EP 3779442A4
ROCCHITTA, G. ET AL.: "Enzyme Biosensors for Biomedical Applications Strategies for Safeguarding Analytical Performances in Biological Fluids", SENSORS, vol. 16, no. 780, 2016, pages 1 - 21, XP055641156
See also references of EP 3779442A4
Attorney, Agent or Firm:
WATANABE Kaoru (JP)
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