Title:
TASTE-MASKED COMPOSITION OF CATIONIC EXCHANGE RESIN
Document Type and Number:
WIPO Patent Application WO2005013934
Kind Code:
A3
Abstract:
The present invention provides a taste-masked composition containing an active compound. The composition is taste-masked by employing a loaded polymeric matrix which is produced by incorporating or complexing the active compound on a polymeric matrix having ionic functional groups and removing unbound active compounds from the polymeric matrix.
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Inventors:
D HARGENS ROBERT (US)
JIA YIMIN (US)
SLOMINSKI GREG (US)
VAYALAKKADA SURESH (US)
JIA YIMIN (US)
SLOMINSKI GREG (US)
VAYALAKKADA SURESH (US)
Application Number:
PCT/EP2004/008394
Publication Date:
May 19, 2005
Filing Date:
July 27, 2004
Export Citation:
Assignee:
NOVARTIS CONSUMER HEALTH SA (CH)
D HARGENS ROBERT (US)
JIA YIMIN (US)
SLOMINSKI GREG (US)
VAYALAKKADA SURESH (US)
D HARGENS ROBERT (US)
JIA YIMIN (US)
SLOMINSKI GREG (US)
VAYALAKKADA SURESH (US)
International Classes:
A61K47/48; (IPC1-7): A61K47/48
Domestic Patent References:
| WO1992001443A1 | 1992-02-06 | |||
| WO2001070194A1 | 2001-09-27 | |||
| WO2003061709A1 | 2003-07-31 |
Foreign References:
| EP1175915A1 | 2002-01-30 | |||
| EP0943341A1 | 1999-09-22 | |||
| EP0367746A2 | 1990-05-09 |
Other References:
SQUILLANTE E. ET AL: "Extended release chlorpheniramine maleate from polymethacrylate solid dispersions by supercritical fluid processing", DRUG DELIVERY TECHNOLOGY, vol. 2, no. 5, August 2002 (2002-08-01), pages 58 - 64, XP008042992
RUDRARAJU V. S. ET AL: "Ion exchange resinates containing chlorpheniramine maleate", PHARMACEUTICAL RESEARCH, vol. 9, 1992, pages S163, XP008043015
NANDA A. ET AL: "An update on taste masking technologies for oral pharmaceuticals", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 64, no. 1, February 2002 (2002-02-01), pages 10 - 17, XP008043034
AGARWAL R. ET AL: "Studies of ion exchange resin complex of chloroquine phosphate", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 26, no. 7, 2000, pages 773 - 776, XP008043026
BYERS, JOHN A.: "Solvent Polarity and Miscibility", INTERNET ARTICLE, 2003, XP002317825, Retrieved from the Internet [retrieved on 20050215]
RUDRARAJU V. S. ET AL: "Ion exchange resinates containing chlorpheniramine maleate", PHARMACEUTICAL RESEARCH, vol. 9, 1992, pages S163, XP008043015
NANDA A. ET AL: "An update on taste masking technologies for oral pharmaceuticals", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 64, no. 1, February 2002 (2002-02-01), pages 10 - 17, XP008043034
AGARWAL R. ET AL: "Studies of ion exchange resin complex of chloroquine phosphate", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 26, no. 7, 2000, pages 773 - 776, XP008043026
BYERS, JOHN A.: "Solvent Polarity and Miscibility", INTERNET ARTICLE, 2003, XP002317825, Retrieved from the Internet
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