Title:
TAXOL DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1998/022451
Kind Code:
A1
Abstract:
Substituted taxol derivatives of general formula (I) having an antitumor activity, wherein R?6� is optionally substituted alkyl, alkenyl or alkynyl; and R?5� is methyl, or together with R?4� forms a three-membered ring, provided the cases wherein R?3� is hydrogen, R?4� is hydrogen or hydroxyl, and the linkage between the carbon atoms to which R?3� and R?4� are bonded respectively is a single bond are excepted.
Inventors:
SOGA TSUNEHIKO (JP)
UOTO KOUICHI (JP)
IIMURA SHIN (JP)
UOTO KOUICHI (JP)
IIMURA SHIN (JP)
Application Number:
PCT/JP1997/004175
Publication Date:
May 28, 1998
Filing Date:
November 17, 1997
Export Citation:
Assignee:
DAIICHI SEIYAKU CO (JP)
SOGA TSUNEHIKO (JP)
UOTO KOUICHI (JP)
IIMURA SHIN (JP)
SOGA TSUNEHIKO (JP)
UOTO KOUICHI (JP)
IIMURA SHIN (JP)
International Classes:
C07D305/14; (IPC1-7): C07D305/14; A61K31/335
Foreign References:
JPH08291156A | 1996-11-05 | |||
JPH07304761A | 1995-11-21 | |||
JPH06179665A | 1994-06-28 |
Attorney, Agent or Firm:
Hagino, Taira (28th floor ARK Mori Building, 12-32, Akasaka 1-chom, Minato-ku Tokyo 107, JP)
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