Title:
TCR MOLECULE BINDING TO SSX2 ANTIGEN AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/241391
Kind Code:
A1
Abstract:
The present invention provides a TCR molecule binding to an SSX2 antigen and an application thereof. The TCR molecule can specifically bind to an SSX2 antigen short peptide complex AQIPEIQK-HLA A1101. Meanwhile, effector cells transducing the TCR further have a very strong killing function.
Inventors:
ZHAN KAI (CN)
YANG DONGXUE (CN)
LIU MIN (CN)
YIN QIANXIA (CN)
WANG DINGGUO (CN)
TANG XIANQING (CN)
MA RUIJUAN (CN)
YANG DONGXUE (CN)
LIU MIN (CN)
YIN QIANXIA (CN)
WANG DINGGUO (CN)
TANG XIANQING (CN)
MA RUIJUAN (CN)
Application Number:
PCT/CN2023/098275
Publication Date:
December 21, 2023
Filing Date:
June 05, 2023
Export Citation:
Assignee:
XLIFESC LTD (CN)
International Classes:
C07K14/725; A61K38/17; A61P35/00; A61P37/02; C07K1/00; C07K19/00; C12N5/10; C12N15/12; C12N15/63
Foreign References:
| CN112442119A | 2021-03-05 | |||
| CN106459179A | 2017-02-22 | |||
| CN114524870A | 2022-05-24 | |||
| CA3149010A1 | 2021-02-04 | |||
| CN105683215A | 2016-06-15 |
Other References:
HE YANG-DONG, NI BING, WU YU-ZHANG: "Progress in SSX gene family", IMMUNOLOGICAL JOURNAL, DI-3 JUNYI DAXUE, CHINA, vol. 21, no. 3, S1, 30 December 2015 (2015-12-30), China , pages S35 - S39, XP009551710, ISSN: 1000-8861, DOI: 10.13431/j.cnki.immunol.j.20050169
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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