Title:
TEMPERATURE-, PH- OR SALT CONCENTRATION-SENSITIVE SEPARATION MATERIAL AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2011/118587
Kind Code:
A1
Abstract:
Disclosed are: an UCST-type temperature-responsive polymer compound which responds to a temperature under physiological conditions and has biological functionality; and various uses thereof as a temperature-responsive material. Specifically disclosed is a temperature-responsive material which contains, as an active ingredient, a polymer compound represented by general formula (I) or an addition salt thereof. The temperature-responsive material is characterized by having an upper critical solution temperature within the range of 5-50˚C in an aqueous solution with a salt concentration of at least 1 mM, said aqueous solution having a pH within the range of 3-10.5. (In the formula, m represents an integer of 10 or more; n represents a number satisfying 0.4 ≤ n ≤ 1; R1 represents a hydrogen atom or a succinyl group; and R2 represents a carbamoyl group.)
Inventors:
SHIMADA NAOHIKO (JP)
MARUYAMA ATSUSHI (JP)
MARUYAMA ATSUSHI (JP)
Application Number:
PCT/JP2011/056844
Publication Date:
September 29, 2011
Filing Date:
March 22, 2011
Export Citation:
Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
SHIMADA NAOHIKO (JP)
MARUYAMA ATSUSHI (JP)
SHIMADA NAOHIKO (JP)
MARUYAMA ATSUSHI (JP)
International Classes:
C08F8/30; B01D11/04; B01J20/26; C08F226/02; C12N7/00; C12N11/08
Foreign References:
| JPS60106803A | 1985-06-12 | |||
| JPH04110313A | 1992-04-10 | |||
| JPH10204120A | 1998-08-04 | |||
| JPH10316827A | 1998-12-02 | |||
| JPH07278235A | 1995-10-24 | |||
| JPS60106803A | 1985-06-12 |
Other References:
NAOHIKO SHIMADA ET AL.: "Seiriteki Jokenka de Koon Yokai Soten'i o Shimesu Polyallylamine Yudotai", THE SOCIETY OF POLYMER SCIENCE, JAPAN IYO KOBUNSHI SYMPOSIUM KOEN YOSHISHU, vol. 39, 16 July 2010 (2010-07-16), pages 71 - 72, XP008161877
OKANO, T. ET AL., J. BIOMED. MATER. RES., vol. 27, 1993, pages 1243 - 1251
KIM, Y.-H. ET AL., J. CONTROL. RELEASE, vol. 28, 1994, pages 148 - 152
BUSCALL, R. ET AL., EUR. POLYM. J., vol. 18, 1982, pages 967 - 974
SCHULZ, D.N. ET AL., POLYMER, vol. 27, 1986, pages 1734 - 1742
AOKI, T. ET AL., POLYMER. J., vol. 31, 1999, pages 1185 - 1188
See also references of EP 2551285A4
OKANO, T. ET AL., J. BIOMED. MATER. RES., vol. 27, 1993, pages 1243 - 1251
KIM, Y.-H. ET AL., J. CONTROL. RELEASE, vol. 28, 1994, pages 148 - 152
BUSCALL, R. ET AL., EUR. POLYM. J., vol. 18, 1982, pages 967 - 974
SCHULZ, D.N. ET AL., POLYMER, vol. 27, 1986, pages 1734 - 1742
AOKI, T. ET AL., POLYMER. J., vol. 31, 1999, pages 1185 - 1188
See also references of EP 2551285A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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Claims: