Title:
TETRAHYDROISOQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/001847
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutically acceptable salt of (S)-2-(6-fluorobenzo[d]oxazol-2-yl)-6-methoxy-5-((5-methoxypyridin-2-yl))methoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, a preparation method therefor, a pharmaceutical composition comprising the pharmaceutically acceptable salt thereof, and the use thereof as a therapeutic agent, in particular as an angiotensin II type-2 receptor antagonist.
Inventors:
GUO YANGHUI (CN)
MENG LICHEN (CN)
HUANG XIANGUI (CN)
LIAO WEIWEI (CN)
GONG YONGXIANG (CN)
XU DAIWANG (CN)
HU TAISHAN (CN)
CHEN LEI (CN)
MENG LICHEN (CN)
HUANG XIANGUI (CN)
LIAO WEIWEI (CN)
GONG YONGXIANG (CN)
XU DAIWANG (CN)
HU TAISHAN (CN)
CHEN LEI (CN)
Application Number:
PCT/CN2021/102261
Publication Date:
January 06, 2022
Filing Date:
June 25, 2021
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
HISUN ACCURAY THERAPEUTICS CO LTD (CN)
HISUN ACCURAY THERAPEUTICS CO LTD (CN)
International Classes:
C07D413/14; A61K31/4725; A61P25/04
Domestic Patent References:
| WO2019242599A1 | 2019-12-26 | |||
| WO1993023378A1 | 1993-11-25 | |||
| WO2016113668A1 | 2016-07-21 | |||
| WO2015003223A1 | 2015-01-15 | |||
| WO2013110135A1 | 2013-08-01 | |||
| WO2019242599A1 | 2019-12-26 |
Foreign References:
| CN105358532A | 2016-02-24 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
Download PDF: