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Title:
TETRALIN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/065893
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel low-molecular-weight compound that exhibits agonistic activity on an orexin receptor and is expected to be useful as a prophylactic or therapeutic agent for narcolepsy and the like. The present invention provides a compound represented by formula (I) (each symbol in the formula has the same meaning as in the description) or a pharmaceutically acceptable acid addition salt of the compound, and an orexin receptor agonist containing the compound or a pharmaceutically acceptable acid addition salt of the compound.

Inventors:
NAGASE HIROSHI (JP)
SAITOH TSUYOSHI (JP)
YANAGISAWA MASASHI (JP)
IRUKAYAMA YOKO (JP)
Application Number:
PCT/JP2020/036853
Publication Date:
April 08, 2021
Filing Date:
September 29, 2020
Export Citation:
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Assignee:
UNIV TSUKUBA (JP)
UNIV TEXAS (US)
International Classes:
A61P1/16; A61K31/167; A61K31/18; A61K31/341; A61K31/381; A61K31/40; A61K31/4406; A61K31/47; A61P3/04; A61P3/10; A61P25/00; A61P25/24; A61P31/04; A61P35/00; A61P43/00; C07C233/80; C07C235/54; C07C235/56; C07C237/40; C07C271/36; C07C311/08; C07C311/10; C07C311/11; C07C311/21; C07C311/29; C07C311/32; C07C311/44; C07C311/50; C07D213/71; C07D215/36; C07D295/088; C07D307/16; C07D307/54; C07D307/64; C07D333/62
Domestic Patent References:
WO2005113527A12005-12-01
WO2002100819A12002-12-19
WO2019117148A12019-06-20
WO2016133160A12016-08-25
WO2015088000A12015-06-18
Foreign References:
JPS50108250A1975-08-26
JPH08503228A1996-04-09
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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