Title:
THERAPEUTIC AGENT FOR DIARRHEA AND METHOD FOR TREATING BOVINE DIARRHEA
Document Type and Number:
WIPO Patent Application WO/2023/100989
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a therapeutic agent for diarrhea having improved therapeutic effect on diarrhea and a method for treating bovine diarrhea. This problem can be solved by a therapeutic agent for diarrhea that contains a bacterium, said therapeutic agent for diarrhea containing at least one type of bacterium selected from the group consisting of 13 types of bacteria listed in Bacterial classification Nos. 1-13 in TABLE 1, wherein the 13 types of bacteria listed in Bacterial classification Nos. 1 to 13 contain sequences that respectively have 95% or more sequence identity to DNA sequences encoding the 16S rRNAs represented by SEQ ID NOS: 1-13.
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Inventors:
NOCHI TOMONORI (JP)
ISLAM JAHIDUL (JP)
TANAKA HIDEKAZU (JP)
ISLAM JAHIDUL (JP)
TANAKA HIDEKAZU (JP)
Application Number:
PCT/JP2022/044458
Publication Date:
June 08, 2023
Filing Date:
December 01, 2022
Export Citation:
Assignee:
UNIV TOHOKU (JP)
CHIBA PREFECTURAL AGRICULTURAL MUTUAL AID ASS (JP)
CHIBA PREFECTURAL AGRICULTURAL MUTUAL AID ASS (JP)
International Classes:
A61K35/741; A61K35/74; A61P1/12; C12N1/20
Domestic Patent References:
| WO2020150672A2 | 2020-07-23 | |||
| WO2020150712A1 | 2020-07-23 | |||
| WO2021183701A1 | 2021-09-16 |
Foreign References:
| JP2020530493A | 2020-10-22 |
Other References:
HIDEKAZU TANAKA, NATSUKI OTANI, MASATO KIKUCHI, YU SHIMIZU: "Review of effectiveness Fecal Microbiota Transplantation (FMT) in Calf with the refractory Diarrhea", THE JOURNAL OF FARM ANIMAL IN INFECTIOUS DISEASE, JAPAN, vol. 9, no. 4, 1 January 2020 (2020-01-01), Japan, pages 93 - 103, XP009546767, ISSN: 2186-7208
TANIMIZU, MASAE ET AL.: "Verification of the effectiveness of fecal microbiota transplantation in calves with intractable diarrhea", JOURNAL OF LIVESTOCK MEDICINE, no. 699, 1 September 2021 (2021-09-01), pages 497 - 504, XP009546764
LEO STEFANO, LAZAREVIC VLADIMIR, GAÏA NADIA, ESTELLAT CANDICE, GIRARD MYRIAM, MATHERON SOPHIE, ARMAND-LEFÈVRE LAURENCE, ANDREMONT : "The intestinal microbiota predisposes to traveler’s diarrhea and to the carriage of multidrug-resistant Enterobacteriaceae after traveling to tropical regions", GUT MICROBES, LANDES BIOSCIENCE, UNITED STATES, vol. 10, no. 5, 3 September 2019 (2019-09-03), United States , pages 631 - 641, XP093070016, ISSN: 1949-0976, DOI: 10.1080/19490976.2018.1564431
POP MIHAI, PAULSON JOSEPH N., CHAKRABORTY SUBHRA, ASTROVSKAYA IRINA, LINDSAY BRIANNA R., LI SHAN, BRAVO HÉCTOR CORRADA, HARRO CLAY: "Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment", BMC GENOMICS, vol. 17, no. 1, 1 December 2016 (2016-12-01), XP093070018, DOI: 10.1186/s12864-016-2777-0
SUGIYAMA, KENTARO ET AL.: "Exploration of factors contributing to the therapeutic effect of fecal microbial transplantation (FMT) for calf diarrhea", JOURNAL OF LIVESTOCK MEDICINE, no. 704, 1 February 2022 (2022-02-01), pages 111 - 112, XP009546765
TANIMIZU, MASAE ET AL.: "Verification of the effectiveness of fecal microbiota transplantation in calves with intractable diarrhea", JOURNAL OF LIVESTOCK MEDICINE, no. 699, 1 September 2021 (2021-09-01), pages 497 - 504, XP009546764
LEO STEFANO, LAZAREVIC VLADIMIR, GAÏA NADIA, ESTELLAT CANDICE, GIRARD MYRIAM, MATHERON SOPHIE, ARMAND-LEFÈVRE LAURENCE, ANDREMONT : "The intestinal microbiota predisposes to traveler’s diarrhea and to the carriage of multidrug-resistant Enterobacteriaceae after traveling to tropical regions", GUT MICROBES, LANDES BIOSCIENCE, UNITED STATES, vol. 10, no. 5, 3 September 2019 (2019-09-03), United States , pages 631 - 641, XP093070016, ISSN: 1949-0976, DOI: 10.1080/19490976.2018.1564431
POP MIHAI, PAULSON JOSEPH N., CHAKRABORTY SUBHRA, ASTROVSKAYA IRINA, LINDSAY BRIANNA R., LI SHAN, BRAVO HÉCTOR CORRADA, HARRO CLAY: "Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment", BMC GENOMICS, vol. 17, no. 1, 1 December 2016 (2016-12-01), XP093070018, DOI: 10.1186/s12864-016-2777-0
SUGIYAMA, KENTARO ET AL.: "Exploration of factors contributing to the therapeutic effect of fecal microbial transplantation (FMT) for calf diarrhea", JOURNAL OF LIVESTOCK MEDICINE, no. 704, 1 February 2022 (2022-02-01), pages 111 - 112, XP009546765
Attorney, Agent or Firm:
MATSUMOTO Seiji (JP)
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