Title:
THERAPEUTIC AGENT FOR CORNEAL/CONJUNCTIVAL DISORDER
Document Type and Number:
WIPO Patent Application WO/2006/115185
Kind Code:
A1
Abstract:
The purpose is to provide a therapeutic agent for a corneal/conjunctival disorder. A compound represented by the general formula (1) or a salt thereof shows an excellent ameliorating effect in a corneal disorder model, and therefore is useful as a therapeutic agent for a corneal/conjunctival disorder such as dry eye, corneal ulcer, keratitis and conjunctivitis. In the general formula, the ring Y represents a substituted or unsubstituted nitrogenated heterocyclic ring; R1 represents a carboxyl group or a substituted or unsubstituted nitrogenated 5-membered heterocyclic ring; and R2 and R3 independently represent a hydrogen atom, a substituted or unsubstituted alkyl group or a substituted or unsubstituted alkylcarbonyl group.
Inventors:
SHIBAGAKI KEIICHI (JP)
HIRAI SHIN-ICHIRO (JP)
NAKAMURA MASATSUGU (JP)
HIRAI SHIN-ICHIRO (JP)
NAKAMURA MASATSUGU (JP)
Application Number:
PCT/JP2006/308382
Publication Date:
November 02, 2006
Filing Date:
April 21, 2006
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
SHIBAGAKI KEIICHI (JP)
HIRAI SHIN-ICHIRO (JP)
NAKAMURA MASATSUGU (JP)
SHIBAGAKI KEIICHI (JP)
HIRAI SHIN-ICHIRO (JP)
NAKAMURA MASATSUGU (JP)
International Classes:
A61K31/41; A61P27/02
Foreign References:
| JPH10218792A | 1998-08-18 | |||
| JPH09508641A | 1997-09-02 | |||
| JP2001055329A | 2001-02-27 | |||
| JPH0867674A | 1996-03-12 | |||
| JPH0363264A | 1991-03-19 | |||
| JPH0327362A | 1991-02-05 | |||
| JP2000143650A | 2000-05-26 |
Other References:
See also references of EP 1872783A4
Attorney, Agent or Firm:
Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18,
Nishishinsaibashi 1-chome, Chuo-ku, Osaka-sh, Osaka 86, JP)
Download PDF:
Previous Patent: METHOD OF MODIFYING PLANT CHARACTERS
Next Patent: PIPET CLEANING DEVICE AND CLEANING METHOD
Next Patent: PIPET CLEANING DEVICE AND CLEANING METHOD