THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASE AND APPLICATION THEREOF

WIPO Patent Application WO/2019/154195

A1

The present invention relates to a novel therapeutic drug for a neurodegenerative disease and an application thereof. Provided is a novel compound of formula (I). The compound can effectively facilitate the proliferation of neural stem cells in both in vitro and in vivo experiments and can be used as a treatment approach for facilitating neuroregeneration to fight against cognitive decline associated with aging or a neurodegenerative disease.

PEI GANG (CN)
YU BIAO (CN)
HUANG SHICHAO (CN)
CAO XIN (CN)
SHI FUCHUN (CN)
ZHOU YUE (CN)
AN YUQIAN (CN)
LU JING (CN)

PCT/CN2019/073773

August 15, 2019

January 29, 2019

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SHANGHAI DONGXI ZHIHUI BIOLOGICAL MEDICINE CO LTD (CN)

C07H13/02; A61K31/165; A61K31/216; A61P25/00; A61P25/16; A61P25/24; A61P25/28; C07H1/00; C07H15/20

CN104958287A	2015-10-07
CN105906672A	2016-08-31

STEPHANIE GROND , INA PAPASTAVROU ,AXEL ZEECK: "Novel alpha-L-Rhamnopyranosides from a Single Strain of Streptomyces by Supplement-Induced Biosynthetic Steps", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY , vol. 2002, no. 19, 20 September 2002 (2002-09-20), pages 3237 - 3242, XP055640358, DOI: 10.1002/1099-0690(200210)2002:19<3237::AID-EJOC3237>3.0.CO;2-T
J. SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 2002, SCIENCE PRESS

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