Title:
THERMOSTABLE GLUCOCEREBROSIDASE
Document Type and Number:
WIPO Patent Application WO/2021/235023
Kind Code:
A1
Abstract:
To provide a protein having glucocerebrosidase activity and also having thermostability. The aforementioned problem is solved by a protein that is plant-derived, belongs to the glycoside hydrolase family 1 (GH1), and has glucocerebrosidase activity.
Inventors:
KOGA JINICHIRO (JP)
YAMANE HISAKAZU (JP)
MIYAMOTO KOJI (JP)
YAZAWA MAKOTO (JP)
KUBOTA TOMOYOSHI (JP)
YAMANE HISAKAZU (JP)
MIYAMOTO KOJI (JP)
YAZAWA MAKOTO (JP)
KUBOTA TOMOYOSHI (JP)
Application Number:
PCT/JP2021/004999
Publication Date:
November 25, 2021
Filing Date:
February 10, 2021
Export Citation:
Assignee:
UNIV TEIKYO (JP)
International Classes:
C12N15/56; A23L33/115; A61K36/28; A61K36/31; A61K36/42; A61K36/48; A61K36/73; A61K36/81; A61K36/88; A61K36/896; A61K36/899; A61K38/47; A61P1/16; A61P3/00; A61P7/04; A61P7/06; A61P19/08; A61P43/00; C07K14/415; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/24; C12N15/29; C12N15/63; C12P21/02
Foreign References:
| JP2013527753A | 2013-07-04 | |||
| JP2020088950A | 2020-06-04 |
Other References:
DATABASE PROTEIN 11 December 2019 (2019-12-11), ANONYMOUS : "RecName: Full=Beta-glucosidase 6; Short=Os3bglu6; Flags: Precursor ", XP055874549, retrieved from UNIPROT Database accession no. Q8L7J2
DATABASE PROTEIN 13 February 2019 (2019-02-13), ANONYMOUS : "Beta-glucosidase 40 isoform A [Glycine soja] ", XP055874557, retrieved from GENBANK Database accession no. RZB42136
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, vol. 4, 2003, pages 403 - 436
BRITISH JOURNAL OF HAEMATOLOGY, vol. 129, 2005, pages 178 - 188
THE JOURNAL OF ANTIBIOTICS, vol. 41, 1988, pages 469 - 480
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282, 2007, pages 30889 - 30900
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 295, 2020, pages 717 - 728
See also references of EP 4155407A4
DATABASE PROTEIN 13 February 2019 (2019-02-13), ANONYMOUS : "Beta-glucosidase 40 isoform A [Glycine soja] ", XP055874557, retrieved from GENBANK Database accession no. RZB42136
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, vol. 4, 2003, pages 403 - 436
BRITISH JOURNAL OF HAEMATOLOGY, vol. 129, 2005, pages 178 - 188
THE JOURNAL OF ANTIBIOTICS, vol. 41, 1988, pages 469 - 480
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282, 2007, pages 30889 - 30900
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 295, 2020, pages 717 - 728
See also references of EP 4155407A4
Attorney, Agent or Firm:
MIGITA, Shunsuke et al. (JP)
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