Title:
THERMOTHERAPY VIA TARGETED DELIVERY OF NANOSCALE MAGNETIC PARTICLES
Document Type and Number:
WIPO Patent Application WO2003022360
Kind Code:
A3
Abstract:
Disclosed are therapeutic methods for the treatment of diseased, disease-causing, or undesirable tissue or material that involve the administration of a thermotherpeutic magnetic composition, which contains single-domain magnetic particles attached to a target-specific ligand, to a patient and the application of an alternating magnetic field to inductively heat the thermotherapeutic magnetic composition. Also disclosed are methods for administration of the thermotherapeutic magnetic composition. These therapeutic methods may be used where the predetermined target is associated with a disease, such as cancer, diseases of the immune system, pathogen-borne diseases, obesity, hormone-related diseases, Alzheimer's disease, disease precursor, and undesirable materials, such as undesirable adipose tissue, reactions to organ transplants, HIV infected cells, polypeptides receptors, blood clots, and low density lipoproteins.
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Inventors:
HANDY ERIK S
IVKOV ROBERT
ELLIS-BUSBY DIANE
FOREMAN ALLAN
BRAUNHUT SUSAN J
GWOST DOUGLAS U
ARDMAN BLAIR
JAHNGEN EDWIN G E
IVKOV ROBERT
ELLIS-BUSBY DIANE
FOREMAN ALLAN
BRAUNHUT SUSAN J
GWOST DOUGLAS U
ARDMAN BLAIR
JAHNGEN EDWIN G E
Application Number:
PCT/US2002/023650
Publication Date:
November 13, 2003
Filing Date:
July 25, 2002
Export Citation:
Assignee:
TRITON BIOSYSTEMS INC (US)
International Classes:
A61F7/00; A61K9/28; A61K9/10; A61K39/395; A61K41/00; A61K45/08; A61K47/10; A61K47/12; A61K47/22; A61K47/32; A61K47/34; A61K47/36; A61K47/42; A61K47/46; A61K47/48; A61N1/40; A61N2/02; A61N2/04; A61P3/06; A61P9/00; A61P19/02; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P31/18; A61P35/00; A61P35/04; A61P37/00; (IPC1-7): A61N2/02; A61N1/40
Domestic Patent References:
| WO2001037721A2 | 2001-05-31 | |||
| WO2001010501A1 | 2001-02-15 | |||
| WO2001017611A1 | 2001-03-15 |
Foreign References:
| US4545368A | 1985-10-08 | |||
| US5300750A | 1994-04-05 | |||
| EP0333381A2 | 1989-09-20 | |||
| EP0543498A1 | 1993-05-26 | |||
| US5067952A | 1991-11-26 | |||
| EP0400940A2 | 1990-12-05 |
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