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Title:
THIADIAZOLYL DERIVATIVES, COMPOSITIONS, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/099337
Kind Code:
A1
Abstract:
The disclosure relates to thiadiazolyl derivatives, for example, a compound of Formula (I), and pharmaceutical compositions thereof. The disclosure also relates to their uses in the treatment of a PolQ-mediated disease, e.g., cancer containing a DNA repair defect.

Inventors:
ZHUO JINCONG (CN)
ZHANG YAO (CN)
ZHOU WENLAI (CN)
Application Number:
PCT/CN2023/130329
Publication Date:
May 16, 2024
Filing Date:
November 08, 2023
Export Citation:
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Assignee:
DANATLAS PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D285/04; A61K31/433; A61P35/00; C07D417/12
Domestic Patent References:
WO2023050007A12023-04-06
WO2023060573A12023-04-20
WO2023061415A12023-04-20
WO2023067515A12023-04-27
WO2023202623A12023-10-26
WO2022118210A12022-06-09
Foreign References:
US20140221411A12014-08-07
CN114127062A2022-03-01
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