Title:
THREE-DIMENSIONAL BASE CALLING IN NEXT GENERATION SEQUENCING ANALYSIS
Document Type and Number:
WIPO Patent Application WO/2024/077165
Kind Code:
A3
Abstract:
Disclosed herein are system, apparatus, method, and/or computer program product embodiments, and/or combinations and sub-combinations thereof which enables 3D base calling using flow cell images of samples such as in situ cells or tissue to ensure accurate base calling and sequencing analysis of 3D samples. Embodiments of the methods, systems, and media for 3D base calling of flow cell images includes image intensity, location, size, and/or of clusters or polonies to be relied on for accurate base calling.
Inventors:
THOMPSON CONNOR (US)
LIU TSUNG-LI (US)
KRUGLYAK SEMYON (US)
LIU TSUNG-LI (US)
KRUGLYAK SEMYON (US)
Application Number:
PCT/US2023/076125
Publication Date:
May 16, 2024
Filing Date:
October 05, 2023
Export Citation:
Assignee:
ELEMENT BIOSCIENCES INC (US)
International Classes:
G16B30/00; C12N15/62; C12Q1/68; G06T7/66; G06V20/69; G01N15/0227
Attorney, Agent or Firm:
HOLOUBEK, Michelle K. et al. (US)
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