Title:
THREE-DIMENSIONAL SCAFFOLD FOR SKIN RESTORATION
Document Type and Number:
WIPO Patent Application WO/2023/075203
Kind Code:
A1
Abstract:
A biodegradable 3D scaffold for skin restoration according to the present invention includes polyethylene glycol-vinylsulfone (PEG-VS), a crosslinking agent, and MFG-E8. When used as a covering material for skin wounds, the 3D scaffold for skin restoration of the present invention can restore the skin while being decomposed in vivo.
Inventors:
LEE SEUNG-TAE (KR)
Application Number:
PCT/KR2022/015263
Publication Date:
May 04, 2023
Filing Date:
October 11, 2022
Export Citation:
Assignee:
KANGWON NATIONAL UNIV INDUSTRY COOPERATION FOUNDATION (KR)
International Classes:
A61L27/60; A61K9/06; A61L27/18; A61L27/22; A61L27/54; A61L27/56; A61P17/02
Foreign References:
| KR20180047433A | 2018-05-10 | |||
| KR102264607B1 | 2021-06-14 | |||
| KR102172344B1 | 2020-11-03 |
Other References:
GONG ZHE, WANG CHENGGUI, NI LICHENG, YING LIWEI, SHU JIAWEI, WANG JINGKAI, YU CHAO, XIA KAISHUN, CHENG FENG, SHI KESI, XU GUOPING,: "An injectable recombinant human milk fat globule–epidermal growth factor 8–loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death", CYTOTHERAPY, vol. 22, no. 4, 1 April 2020 (2020-04-01), GB , pages 193 - 203, XP093060799, ISSN: 1465-3249, DOI: 10.1016/j.jcyt.2020.01.016
ADELOW, C. SEGURA, T. HUBBELL, J.A. FREY, P.: "The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype", BIOMATERIALS, vol. 29, no. 3, 22 October 2007 (2007-10-22), AMSTERDAM, NL , pages 314 - 326, XP022338914, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2007.09.036
ADELOW, C. SEGURA, T. HUBBELL, J.A. FREY, P.: "The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype", BIOMATERIALS, vol. 29, no. 3, 22 October 2007 (2007-10-22), AMSTERDAM, NL , pages 314 - 326, XP022338914, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2007.09.036
Attorney, Agent or Firm:
CHOI, Jung-moon (KR)
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