Title:
THYMOSIN ALPHA 1 PEPTIDE/POLYMER CONJUGATES
Document Type and Number:
WIPO Patent Application WO2003037272
Kind Code:
A3
Abstract:
A pharmaceutical composition includes a physiologically active conjugate including a Thymosin alpha 1 (TA1) peptide conjugated to a material which increases half-life of the TA1 peptide in serum of a patient when the conjugate is administered to a patient. The material may be a substantially non-antigenic polymer. In a method of the invention, the substantially non-antigenic polymer is conjugated to a TA1 peptide. Compositions according to the invention are administered to patients in need of immune stimulation.
Inventors:
RUDOLPH ALFRED R (US)
TUTHILL CYNTHIA W (US)
TUTHILL CYNTHIA W (US)
Application Number:
PCT/US2002/035094
Publication Date:
November 20, 2003
Filing Date:
November 01, 2002
Export Citation:
Assignee:
SCICLONE PHARMACEUTICALS INC (US)
RUDOLPH ALFRED R (US)
TUTHILL CYNTHIA W (US)
RUDOLPH ALFRED R (US)
TUTHILL CYNTHIA W (US)
International Classes:
A61K38/22; A61K47/48; A61P37/04; (IPC1-7): A61K38/16; A61K38/17; A61K38/22; C07K14/00; C07K14/435; C07K14/575
Domestic Patent References:
| WO1994013314A1 | 1994-06-23 |
Foreign References:
| US4079127A | 1978-03-14 | |||
| US4179337A | 1979-12-18 | |||
| US6309633B1 | 2001-10-30 | |||
| US4353821A | 1982-10-12 |
Other References:
See also references of EP 1455766A4
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