TIGHT JUNCTION FORMATION INDUCER

Title:

TIGHT JUNCTION FORMATION INDUCER

Document Type and Number:

WIPO Patent Application WO/2020/256110

Kind Code:

A1

Abstract:

The present disclosure provides a tight junction formation inducer/composition containing, as an active ingredient, a substance that promotes the accumulation of claudin at an intercellular adhesion site.

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Inventors:

ODA YUKAKO (JP)
TOYOSHIMA FUMIKO (JP)
ISHIHAMA YASUSHI (JP)

Application Number:

PCT/JP2020/024154

Publication Date:

December 24, 2020

Filing Date:

June 19, 2020

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Assignee:

UNIV KYOTO (JP)

International Classes:

A61K38/08; A61K45/00; A61K38/57; A61P17/00; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P37/08; A61P43/00; C07K7/06

Foreign References:

JP2018155538A	2018-10-04
JP2015514127A	2015-05-18
JP2019502668A	2019-01-31
US20110117106A1	2011-05-19

Other References:

SATOHISA, S. ET AL.: "Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4a-induced epithelial polarization", EXPERIMENTAL CELL RESEARCH, vol. 310, 2005, pages 66 - 78, XP005093307, DOI: 10.1016/j.yexcr.2005.06.025
IKENOUCHI, JUNICHI: "Elucidation of molecular mechanisms involved in the formation of tight junction", ANNUAL REPORT OF COSMETOLOGY, vol. 25, 2017, pages 42 - 45

Attorney, Agent or Firm:

YAMAO, Norihito et al. (JP)

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