Title:
TOLEROGENIC SYNTHETIC NANOCARRIERS FOR REGULATING INNATE IMMUNE RESPONSES
Document Type and Number:
WIPO Patent Application WO/2012/149405
Kind Code:
A3
Abstract:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering B cell and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to reduce antigen- specific activation of innate immune cells.
Inventors:
MALDONADO ROBERTO A (US)
Application Number:
PCT/US2012/035574
Publication Date:
March 21, 2013
Filing Date:
April 27, 2012
Export Citation:
Assignee:
SELECTA BIOSCIENCES INC (US)
MALDONADO ROBERTO A (US)
MALDONADO ROBERTO A (US)
International Classes:
A61K47/48; A61K9/127; A61K39/00; A61K39/38; A61K47/30
Domestic Patent References:
| WO2010138192A2 | 2010-12-02 |
Foreign References:
| US20100183727A1 | 2010-07-22 | |||
| US20100151000A1 | 2010-06-17 | |||
| US20110070154A1 | 2011-03-24 | |||
| US20100008932A1 | 2010-01-14 |
Attorney, Agent or Firm:
VATLAND, Janice A. (P.C.600 Atlantic Avenu, Boston MA, US)
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