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Title:
TOOTH SURFACE TREATING AGENT AND TOOTH SURFACE TREATING KIT
Document Type and Number:
WIPO Patent Application WO/2023/063076
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a tooth surface treating agent and a tooth surface treating kit, with which a uniform and high-strength layer formed of apatite is formed on a tooth surface to restore fine recesses in the tooth surface. This tooth surface treating agent contains: a liquid containing an organic acid and having a pH of 1.0-3.0; and hydroxyapatite particles having a particle diameter of at most 200 nm. Moreover, this tooth surface treating kit contains: a first treating agent which is a liquid containing an organic acid and having a pH of 1.0-3.0, and stored in a first container; and a second treating agent which is hydroxyapatite particles having a particle diameter of at most 200 nm, and stored in a second container different from the first container, wherein a tooth surface treating agent prepared by mixing the first treating agent and the second treating agent is applied onto a tooth surface to be treated.

Inventors:
NISHIO HIDETOSHI (JP)
MIKI NAOKO (JP)
Application Number:
PCT/JP2022/036088
Publication Date:
April 20, 2023
Filing Date:
September 28, 2022
Export Citation:
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Assignee:
NISHIO CO LTD (JP)
International Classes:
A61K6/20; A61K6/60; A61K6/75; A61K8/365; A61K8/55
Domestic Patent References:
WO2020222306A12020-11-05
WO2006039278A22006-04-13
Foreign References:
JP2012077009A2012-04-19
JPH11116421A1999-04-27
Other References:
AKANE YASHIMA; INUKAI, JUNKO; MUKAI, MASAMI: "Effect of type of acid and pH and immersion time on enamel hardness", JOURNAL OF DENTAL HEALTH, vol. 65, no. 1, 1 January 2015 (2015-01-01), JP , pages 2 - 9, XP009545278, ISSN: 0023-2831, DOI: 10.5834/jdh.65.1_2
CHIBA TOSHIE, ASADA YUKA, ISHIKAWA MISAO, YAMAMOTO TAKATSUGU, SHIMODA SHINJI, MOMOI YASUKO: "Remineralization Effects of Calcium Phosphate Based Paste for Tooth Enamel", THE JAPANESE JOURNAL OF CONSERVATIVE DENTISTRY, vol. 59, no. 1, 1 January 2016 (2016-01-01), JP , pages 58 - 64, XP093056468, ISSN: 0387-2343, DOI: 10.11471/shikahozon.59.58
DEGLI ESPOSTI LORENZO, ADAMIANO ALESSIO, TAMPIERI ANNA, RAMIREZ-RODRIGUEZ GLORIA BELEN, SILIQI DRITAN, GIANNINI CINZIA, IVANCHENKO: "Combined Effect of Citrate and Fluoride Ions on Hydroxyapatite Nanoparticles", CRYSTAL GROWTH & DESIGN, vol. 20, no. 5, 6 May 2020 (2020-05-06), US , pages 3163 - 3172, XP093056471, ISSN: 1528-7483, DOI: 10.1021/acs.cgd.0c00038
Attorney, Agent or Firm:
KAIZUKA, Ryohei et al. (JP)
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