Title:
TOPICAL FORMULATION CONTAINING PIRFENIDONE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/051687
Kind Code:
A1
Abstract:
A pirfenidone topical formulation is provided, comprising a therapeutically effective amount of pirfenidone, water, and at least one cosolvent, the cosolvent being selected from a combination of dimethyl sulfoxide and an alcohol solvent. The formulation exhibits high skin permeability, good stability, no irritation, excellent skin tolerance, and ease of use. The formulation can be used in the preparation of drugs for preventing or treating diseases related to excessive proliferation of skin or connective tissues and chronic skin injuries.
Inventors:
LIU FEI (CN)
JIANG WEIHUA (CN)
SHI LI (CN)
LI PEIRAN (CN)
CAO XIAOQIN (CN)
DU ZIDIE (CN)
WANG JIE (CN)
ZHANG CUIXIA (CN)
JIANG WEIHUA (CN)
SHI LI (CN)
LI PEIRAN (CN)
CAO XIAOQIN (CN)
DU ZIDIE (CN)
WANG JIE (CN)
ZHANG CUIXIA (CN)
Application Number:
PCT/CN2023/116997
Publication Date:
March 14, 2024
Filing Date:
September 05, 2023
Export Citation:
Assignee:
NANJING MINOVA PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K9/00; A61K9/06; A61K9/08; A61K31/4412; A61P17/00
Domestic Patent References:
| WO2004058256A1 | 2004-07-15 | |||
| WO2021022033A1 | 2021-02-04 |
Foreign References:
| MX2019007860A | 2020-12-29 | |||
| CN113056257A | 2021-06-29 | |||
| CN102670632A | 2012-09-19 |
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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