Title:
TRANSDERMAL ABSORPTION PREPARATION
Document Type and Number:
WIPO Patent Application WO/2021/166987
Kind Code:
A1
Abstract:
The present invention pertains to a transdermal absorption preparation that is capable of maintaining a blood concentration sufficient to exert the medicinal effect of tandospirone and that has excellent storage stability against heat, humidity and light. The present invention makes it possible to provide a transdermal absorption preparation characterized by comprising tandospirone or a pharmaceutically acceptable salt thereof and levulinic acid. This transdermal absorption preparation of tandospirone exhibits high skin permeability of tandospirone or a pharmaceutically acceptable salt thereof contained in the preparation and has excellent storage stability against heat and light.
Inventors:
ICHIBAYASHI ERI (JP)
TANAKA MASAYASU (JP)
IKEDA YUKI (JP)
TAKITA TOMOHITO (JP)
TAMURA KEI (JP)
NAKAMURA TETSUYA (JP)
FUJIWARA KAIJI (JP)
TANAKA MASAYASU (JP)
IKEDA YUKI (JP)
TAKITA TOMOHITO (JP)
TAMURA KEI (JP)
NAKAMURA TETSUYA (JP)
FUJIWARA KAIJI (JP)
Application Number:
PCT/JP2021/006052
Publication Date:
August 26, 2021
Filing Date:
February 18, 2021
Export Citation:
Assignee:
SUMITOMO DAINIPPON PHARMA CO LTD (JP)
International Classes:
A61K31/496; A61K9/70; A61K31/19; A61K31/506; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/22; A61P25/22; A61P43/00
Domestic Patent References:
| WO2010016219A1 | 2010-02-11 | |||
| WO2017037812A1 | 2017-03-09 | |||
| WO2005117886A1 | 2005-12-15 | |||
| WO2008044336A1 | 2008-04-17 |
Foreign References:
| JPH11228414A | 1999-08-24 | |||
| JP2006169238A | 2006-06-29 | |||
| JPH1179979A | 1999-03-23 | |||
| JP2017522285A | 2017-08-10 | |||
| JP2006241179A | 2006-09-14 | |||
| JPS58126865A | 1983-07-28 | |||
| JP2020026337A | 2020-02-20 | |||
| JP2020132798A | 2020-08-31 |
Other References:
ANONYMOUS: "Tandospirone", DRUGBANK, 1 January 1900 (1900-01-01), pages 1 - 4, XP055849780, Retrieved from the Internet
"Japanese Pharmacopoeia"
See also references of EP 4108243A4
"Japanese Pharmacopoeia"
See also references of EP 4108243A4
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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