Title:
TRANSFER SYSTEM-BASED HIGH-SENSITIVITY SENSOR
Document Type and Number:
WIPO Patent Application WO/2020/190061
Kind Code:
A1
Abstract:
The present invention relates to: a binding agent-polynucleotide conjugate comprising a specific binding agent and a polynucleotide, which includes a sequence for encoding a light-up aptamer; and a composition and a method for detecting a target substance by using same.
Inventors:
SHIN YONG BEOM (KR)
BYUN JU YOUNG (KR)
SIM JI EUN (KR)
JO NA REA (KR)
BYUN JU YOUNG (KR)
SIM JI EUN (KR)
JO NA REA (KR)
Application Number:
PCT/KR2020/003796
Publication Date:
September 24, 2020
Filing Date:
March 19, 2020
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
BIONANO HEALTH GUARD RES CENTER (KR)
BIONANO HEALTH GUARD RES CENTER (KR)
International Classes:
G01N33/543; G01N33/58
Foreign References:
| US20120252699A1 | 2012-10-04 | |||
| EP3211083A1 | 2017-08-30 | |||
| KR20150080417A | 2015-07-09 | |||
| KR20120025226A | 2012-03-15 |
Other References:
NEUBACHER, SASKIA ET AL.: "RNA structure and cellular applications of fluorescent light-up aptamers", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 58, no. 5, 5 November 2018 (2018-11-05), pages 1266 - 1279, XP055741164
PASSARIELLO, MARGHERITA ET AL.: "Novel human bispecific aptamer-antibody conjugates for efficient cancer cell killing", CANCERS, vol. 11, 29 August 2019 (2019-08-29), pages 1 - 20, XP055741168
PASSARIELLO, MARGHERITA ET AL.: "Novel human bispecific aptamer-antibody conjugates for efficient cancer cell killing", CANCERS, vol. 11, 29 August 2019 (2019-08-29), pages 1 - 20, XP055741168
Attorney, Agent or Firm:
BAE, KIM & LEE IP GROUP (KR)
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