Title:
TRANSFORMANT, AND METHOD FOR PRODUCING 1,3-BUTANEDIOL USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/049616
Kind Code:
A1
Abstract:
Provided are: a transformant which can produce 1,3-butanediol in a biological manner; and a method for producing 1,3-butanediol using the transformant. In one aspect, a transformant produced by introducing a gene encoding an alcohol dehydrogenase belonging to the cinnamyl-alcohol dehydrogenase (CAD) family into a host bacterium, wherein the host bacterium has a mutant or a gene introduced thereinto in such a manner that at least one of the enzymes (A) to (D) can be expressed or the expression of the at least one of the enzymes can be induced. (A) Acetyl-CoA carboxylase; (B) acetyl-CoA synthetase; (C) acetyl-CoA reductase; and (D) 3-3-hydroxybutyryl-CoA reductase.
Inventors:
INUI MASAYUKI
HIRAGA KAZUMI
SUDA MASAKO
KATO NAOTO
WATANABE AKIRA
OIDE SHINICHI
HIRAGA KAZUMI
SUDA MASAKO
KATO NAOTO
WATANABE AKIRA
OIDE SHINICHI
Application Number:
PCT/JP2020/034469
Publication Date:
March 18, 2021
Filing Date:
September 11, 2020
Export Citation:
Assignee:
RESEARCH INSTITUTE OF INNOVATIVE TECH FOR THE EARTH (JP)
GREEN EARTH INST CO LTD (JP)
GREEN EARTH INST CO LTD (JP)
International Classes:
C12P7/18; C12N1/21; C12N15/52; C12N15/53
Domestic Patent References:
| WO2016168247A1 | 2016-10-20 | |||
| WO2014045781A1 | 2014-03-27 |
Foreign References:
| JP2012525158A | 2012-10-22 | |||
| JP2016500261A | 2016-01-12 | |||
| JP2018530342A | 2018-10-18 | |||
| JP2018519829A | 2018-07-26 |
Attorney, Agent or Firm:
IKEUCHI & PARTNERS (JP)
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