Title:
TRANSGENICALLY PRODUCED PLATELET DERIVED GROWTH FACTOR
Document Type and Number:
WIPO Patent Application WO2001098520
Kind Code:
A8
Abstract:
The invention features transgenically produced PDGF, e.g., transgenically produced PDGF which is expressed in the milk of a transgenic mammal, and is present in the milk in active form, e.g., as a dimer. The invention also features methods of producing transgenic PDGF, transgenic animals capable of expressing PDGF, and nucleic acid sequences encoding PDGF, e.g., nucleic acid sequences encoding PDGF, under the control of a mammary gland specific promoter.
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Inventors:
ECHELARD YANN (US)
MEADE HARRY (US)
EICHNER WOLFRAM (DE)
SOMMERMEYER KLAUS (DE)
MEADE HARRY (US)
EICHNER WOLFRAM (DE)
SOMMERMEYER KLAUS (DE)
Application Number:
PCT/US2001/041044
Publication Date:
March 27, 2003
Filing Date:
June 19, 2001
Export Citation:
Assignee:
GENZYME TRANSGENICS CORP (US)
ECHELARD YANN (US)
MEADE HARRY (US)
EICHNER WOLFRAM (DE)
SOMMERMEYER KLAUS (DE)
ECHELARD YANN (US)
MEADE HARRY (US)
EICHNER WOLFRAM (DE)
SOMMERMEYER KLAUS (DE)
International Classes:
C07K14/49; C12N15/09; A61K38/00; (IPC1-7): C12P21/00; A01K67/00; C12N15/00; C07H21/04; A61K38/24; A23C/
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