TREATMENT OF CONJUNCTIVITIS

WIPO Patent Application WO2001015719

A3

The present invention relates to the discovery that various proteins isolated from ticks are effective in the treatment of conjunctivitis. These proteins may most suitably be applied topically to an affected area and are effective to ameliorate the symptoms of this conditions.

WO/2001/038522	A NOVEL POLYPEPTIDE, A HUMAN HISTONE H2A.21 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
WO/2002/000866	A NEW POLYPEPTIDE- HUMAN I CLASS AMINOACYL-TRNA SYNTHETASE 10 AND THE POLYNUCLEOTIDE ENCODING IT
WO/2001/048159	A NEW POLYPEPTIDE-DIHYDROOROTASE 9 AND THE POLYNUCLEOTIDE ENCODING IT

NUTTALL PATRICIA ANNE (GB)
PAESEN GUIDO CHRISTIAAN (GB)

PCT/GB2000/003282

May 10, 2001

August 24, 2000

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EVOLUTEC LTD (GB)
NUTTALL PATRICIA ANNE (GB)
PAESEN GUIDO CHRISTIAAN (GB)

A61K38/17; A61P27/02; A61K38/00; A61P27/14; A61P29/00; (IPC1-7): A61K38/17; A61P37/08

WO1997044451A2	1997-11-27
WO1999027104A1	1999-06-03

BISCA M: "Current therapy of allergic conjunctivitis", CURRENT THERAPEUTIC RESEARCH, vol. 58, no. 11, November 1997 (1997-11-01), pages 828 - 841, XP000982298
KUNKEL GERT: "Therapy of allergic rhinoconjunctivitis: Topic and/or systemic application", ALLERGOLOGIE, vol. 21, no. 4, April 1998 (1998-04-01), pages S37 - S45, XP000982312
CHAPIN M J ET AL: "Evaluation of a histamine binding protein derived from tick saliva in the rabbit model of allergic conjunctivitis.", FASEB JOURNAL, vol. 14, no. 4, 15 March 2000 (2000-03-15), Annual Meeting of Professional Research Scientists: Experimental Biology 2000.;San Diego, California, USA; April 15-18, 2000, pages A183, XP002160669, ISSN: 0892-6638

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