Title:
TREATMENT OF DRUG RESISTANT ORGANISMS WITH NITRIC OXIDE
Document Type and Number:
WIPO Patent Application WO2002020026
Kind Code:
A3
Abstract:
The products of the acidification of nitrite are useful to control multiply drug resistant bacteria, such as methicillin resistant S. aureurs.
Inventors:
BENJAMIN NIGEL (GB)
ORMEROD ANTHONY (GB)
ORMEROD ANTHONY (GB)
Application Number:
PCT/GB2001/004048
Publication Date:
May 16, 2002
Filing Date:
September 10, 2001
Export Citation:
Assignee:
UNIV ABERDEEN (GB)
BENJAMIN NIGEL (GB)
ORMEROD ANTHONY (GB)
BENJAMIN NIGEL (GB)
ORMEROD ANTHONY (GB)
International Classes:
A61K9/06; A61K9/08; A61K9/10; A61K9/107; A61K9/12; A61K9/70; A61K9/72; A61K31/185; A61K31/19; A61K31/191; A61K31/192; A61K31/375; A61K31/43; A61K31/4365; A61K31/545; A61K31/60; A61K33/00; A61K45/06; A61K47/06; A61K47/10; A61K47/24; A61P31/04; A61P43/00; (IPC1-7): A61K33/02; A61K47/12
Domestic Patent References:
| WO1995022335A1 | 1995-08-24 |
Other References:
WELLER R ET AL: "A randomized trial of acidified nitrite cream in the treatment of tinea pedis", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, C.V. MOSBY, ST. LOUIS, MO, US, vol. 38, no. 4, April 1998 (1998-04-01), pages 559 - 563, XP002111730, ISSN: 0190-9622
BOGDAN C C ET AL: "Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity", CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, XX, vol. 12, no. 1, 1 February 2000 (2000-02-01), pages 64 - 76, XP004257620, ISSN: 0952-7915
FANG F C: "MECHANISMS OF NITRIC OXIDE RELATED ANTIMICROBIAL ACTIVITY", JOURNAL OF CLINICAL INVESTIGATION, vol. 99, no. 12, 12 July 1997 (1997-07-12), pages 2818 - 2825, XP002189642
EHLERT K: "METHICILLIN-RESISTANCE IN STAPHYLOCOCCUS AUREUS - MOLECULAR BASIS, NOVEL TARGETS AND ANTIBIOTIC THERAPY", CURRENT PHARMACEUTICAL DESIGN, vol. 5, no. 2, February 1999 (1999-02-01), pages 45 - 55, XP001055322
BOGDAN C C ET AL: "Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity", CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, XX, vol. 12, no. 1, 1 February 2000 (2000-02-01), pages 64 - 76, XP004257620, ISSN: 0952-7915
FANG F C: "MECHANISMS OF NITRIC OXIDE RELATED ANTIMICROBIAL ACTIVITY", JOURNAL OF CLINICAL INVESTIGATION, vol. 99, no. 12, 12 July 1997 (1997-07-12), pages 2818 - 2825, XP002189642
EHLERT K: "METHICILLIN-RESISTANCE IN STAPHYLOCOCCUS AUREUS - MOLECULAR BASIS, NOVEL TARGETS AND ANTIBIOTIC THERAPY", CURRENT PHARMACEUTICAL DESIGN, vol. 5, no. 2, February 1999 (1999-02-01), pages 45 - 55, XP001055322
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