TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST - WUHAN HUMANWELL INNOVATIVE DRUG RES AND DEVELOPMENT CENTER LIMITED COMPANY

Title:

TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST

Document Type and Number:

WIPO Patent Application WO/2024/022314

Kind Code:

A1

Abstract:

The present invention provides a new class of compounds that effectively antagonize LPAR1, which compounds are as shown in the following formula, or stereoisomers, hydrates, solvates, pharmaceutically acceptable salts or prodrugs of the compounds as shown in following formula (I).

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Inventors:

ZHANG XUEJUN (CN)
ZANG YANG (CN)
YANG HUI (CN)
JIA YIMIN (CN)
ZHUO JUNMING (CN)
WANG MENG (CN)
LI LIE (CN)
YANG JUN (CN)

Application Number:

PCT/CN2023/109039

Publication Date:

February 01, 2024

Filing Date:

July 25, 2023

Export Citation:

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Assignee:

WUHAN HUMANWELL INNOVATIVE DRUG RES AND DEVELOPMENT CENTER LIMITED COMPANY (CN)

International Classes:

C07D401/14; A61K31/4439

Domestic Patent References:

WO2022034568A1	2022-02-17
WO2012138648A1	2012-10-11

Foreign References:

CN114456159A	2022-05-10
CN112074515A	2020-12-11
CN112041302A	2020-12-04

Attorney, Agent or Firm:

ZHIFAN & PARTNERS (CN)

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