TRICYCLIC COMPOUNDS AS CDK INHIBITORS AND METHODS OF USING SAME

Title:

TRICYCLIC COMPOUNDS AS CDK INHIBITORS AND METHODS OF USING SAME

Document Type and Number:

WIPO Patent Application WO/2024/067820

Kind Code:

A1

Abstract:

Provided are novel tricyclic compounds as CDK inhibitors, which are useful for treating diseases or conditions mediated by CDKs, particularly cancers and other diseases caused by abnormal cell proliferation. Preparation methods, pharmaceutical compositions and methods of use are also included.

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Inventors:

CAO YEXING (CN)
BAO JIANMING (CN)
YANG HONGJIAN (CN)
BAI CHANG (CN)
QIN JIALIANG (CN)
SU JING (US)
SUN YONGKUI (CN)
XIA NANSONG (CN)

Application Number:

PCT/CN2023/122691

Publication Date:

April 04, 2024

Filing Date:

September 28, 2023

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Assignee:

SHENZHEN IONOVA LIFE SCIENCE CO LTD (CN)
FOSHAN IONOVA BIOTHERAPEUTICS CO INC (CN)
GUANGDONG TOUCHSTONE TRANSLATIONAL RES INSTITUTE CO LTD (CN)

International Classes:

C07D471/14; A61K31/519; A61P35/00; C07D519/00

Domestic Patent References:

WO2018214846A1	2018-11-29
WO2021254384A1	2021-12-23

Foreign References:

CN105481858A	2016-04-13
CN108727368A	2018-11-02

Attorney, Agent or Firm:

BEIJING DINGJIADA IP FIRM (CN)

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