Title:
TRICYCLIC COMPOUNDS AS EGFR INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2021/208918
Kind Code:
A1
Abstract:
Provided are a class of compounds, represented by formula (I"'), as selective EGFR inhibitors, a pharmaceutical composition containing the compounds, useful intermediates for preparing the compounds, and a method for using the compounds of the present invention to treat cell proliferative diseases, such as cancers.
Inventors:
ZHENG SHANSONG (CN)
DENG WEI (CN)
CAMPOS SEBASTIEN ANDRE (CN)
YANG YINGYING (CN)
TIAN ZHENHUA (CN)
ZHENG QINGMEI (CN)
WU GUOSHENG (CN)
ZHAO ZHIWEI (CN)
LI LEILEI (CN)
FU JIANMIN (CN)
ZHAO SHUYONG (CN)
DENG WEI (CN)
CAMPOS SEBASTIEN ANDRE (CN)
YANG YINGYING (CN)
TIAN ZHENHUA (CN)
ZHENG QINGMEI (CN)
WU GUOSHENG (CN)
ZHAO ZHIWEI (CN)
LI LEILEI (CN)
FU JIANMIN (CN)
ZHAO SHUYONG (CN)
Application Number:
PCT/CN2021/086941
Publication Date:
October 21, 2021
Filing Date:
April 13, 2021
Export Citation:
Assignee:
QILU PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D239/48; A61K31/495; A61P35/00; C07D223/14; C07D243/00; C07D313/06; C07D403/14; C07D471/14; C07D487/14; C07D519/00
Foreign References:
| CN101031560A | 2007-09-05 | |||
| CN101535276A | 2009-09-16 | |||
| CN101616895A | 2009-12-30 |
Other References:
DATABASE REGISTRY 21 October 2009 (2009-10-21), ANNONYMOUS: "4H-Pyrazolo[3,4-c]quinolin-4-one, 8-amino-5-ethyl-3,5-dihydro-3-methyl- (CA INDEX NAME)", XP055858250, retrieved from STN Database accession no. 1189306-45-3
See also references of EP 4137484A4
See also references of EP 4137484A4
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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