TRICYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE - STARG WUHAN PHARMACEUTICAL TECH CO LTD

Title:

TRICYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE

Document Type and Number:

WIPO Patent Application WO/2024/066984

Kind Code:

A1

Abstract:

Provided in the present invention is a tricyclic derivative, and the structure thereof is as shown in formula (I). In addition, further disclosed in the present invention are a pharmaceutically acceptable salt of the derivative, a stereoisomer, and a pharmaceutical composition thereof, and the use thereof. The compound of the present invention has a significant CDK12 inhibitory activity and has great practical value.

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Inventors:

HU PU (CN)
LU JUQUAN (CN)

Application Number:

PCT/CN2023/117257

Publication Date:

April 04, 2024

Filing Date:

September 06, 2023

Export Citation:

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Assignee:

STARG WUHAN PHARMACEUTICAL TECH CO LTD (CN)

International Classes:

C07D487/04; A61K31/436; A61K31/4365; A61K31/4985; A61K31/542; A61P35/00; C07D487/14; C07D491/04; C07D495/04

Attorney, Agent or Firm:

ADVANCE CHINA IP LAW OFFICE (CN)

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